ABSTRACT
Twenty-six non-randomized patients with carpal tunnel syndrome are presented. It is documented that three out of four patients may be diagnosed pre-operatively by five or more clinical parameters. All patients were screened for amyloidosis in biopsies from the carpal tunnel. One patient presented amyloid deposits in the transversal carpal ligament. The importance of macro- and microscopic findings in the carpal tunnel inclusive local amyloidosis for the pathogenesis of the carpal tunnel is discussed. It is concluded that provided systemic amyloidosis is not suspected, screening for amyloidosis may have diagnostic interest, however without therapeutic consequences and therefore unnecessary.
Subject(s)
Amyloidosis/diagnosis , Carpal Tunnel Syndrome/diagnosis , Adult , Aged , Amyloidosis/complications , Amyloidosis/pathology , Biopsy , Carpal Tunnel Syndrome/complications , Carpal Tunnel Syndrome/pathology , Electromyography , Female , Humans , Ligaments/pathology , Male , Middle AgedABSTRACT
A well-documented case of solitary extramedullary plasmacytoma located in the small intestine is presented. The patient underwent local resection of the tumor, and shows no signs of local recurrence or dissemination of the disease after a five-year follow-up. The pathologic nature of plasma cell tumors is discussed, and it is concluded that the demonstration of intracytoplasmatic immunoglobulin is essential for the exact classification of plasma cell neoplasms.
