ABSTRACT
It was shown that in patients with hypertension, duodenal and gastric ulcers and erosive gastritis leukopenia and lymphopenia are seen. At the same time contents of T- and B-lymphocytes are decreased and contents of C- lymphocytes are increased in circulation blood. Peroral daily intake of 20 mg of beta-carotene during 3-4 weeks caused increasing the contents of B- and T-cells and decreasing contents of C-lymphocytes in blood of patients.
Subject(s)
Adjuvants, Immunologic/administration & dosage , Carotenoids/administration & dosage , Gastritis/drug therapy , Hypertension/drug therapy , Peptic Ulcer/drug therapy , Administration, Oral , B-Lymphocytes/immunology , Duodenal Ulcer/drug therapy , Gastritis/immunology , Humans , Hypertension/immunology , Lymphocyte Count , Peptic Ulcer/immunology , Stomach Ulcer/drug therapy , T-Lymphocytes/immunology , Time Factors , beta CaroteneABSTRACT
Adequately good consumption of beta-carotene was observed in patients with duodenal ulcer and erosive gastritis after daily treatment with 18 mg of the carotinoid used as 0.1% oil solution: concentration of beta-carotene was increased approximately 3-fold in blood serum of these patients. Concentration of retinol was not increased in blood serum after treatment with beta-carotene, thus indicating that the drug treatment was not dangerous. Treatment with beta-carotene led to improvement in the state of the antioxidative system of these patients as resistance of erythrocytes to peroxide hydrolysis was increased while content of malonic dialdehyde was decreased in blood serum. The carotene treatment contributed to arresting pain syndrome in patients with ulcers, to cicatrization of ulcers and to disappearance of gastric mucosal membrane erosion.
