ABSTRACT
Heating humans up to rectal temperature 39.0-39.5 degrees C induces a heat stress and a physiological adaptation. Blood cells were found to produce nitric oxide under these conditions, neutrophiles playing a major role in the process. In our opinion, the HSC 70 takes part in the process of the long cell adaptation augmenting the cells' functional activity. Hyperthermia leads to a massive temporal HSP 72 expression in the blood mononuclears. This expression seems to be due to alterations in the cellular proteins and to oxidative stress.
Subject(s)
Adaptation, Physiological , Body Temperature Regulation , Hot Temperature/adverse effects , Leukocytes, Mononuclear/metabolism , Adult , Blood Pressure , HSP70 Heat-Shock Proteins/metabolism , Heart Rate , Humans , Immunoenzyme Techniques , Interleukin-2/blood , Male , Nitric Oxide/biosynthesis , Protein Isoforms/metabolism , Respiratory Function TestsSubject(s)
Environmental Health , Work Capacity Evaluation , Adolescent , Adult , Humans , Male , Reference ValuesABSTRACT
The analysis of long standing researches in the military operators' procedure has shown some regularities in the changes of indices which were examined. Varying in time and magnitude the non-specific reactions at first manifest itself in unstable vegetative regulations, then proliferate its influence upon visual and motor coordination, and finally cause negative shifts in professional activities (worsening of accuracy and precision, appearance of errors, etc). It is obvious, that specific reactions impose their own features on the development of this program without changing its basic trend.
Subject(s)
Military Personnel , Physical Fitness/physiology , Electrocardiography , Fatigue/physiopathology , Heart Rate/physiology , Humans , Psychomotor Performance/physiology , Work Capacity EvaluationABSTRACT
In anesthetized cats, a gradual decrement of direct cortical responses was studied in associative and SII cortical areas, in neuronally isolated and in intact cortex. The habituation of direct cortical responses was more rapid in associative area of the intact cortex after deafferentiation of the cerebral hemisphere than in the neuronally isolated cortex. The mechanism of habituation in intact cortex of animals with neuronally isolated cortex is discussed.
