ABSTRACT
Recently, there has been an increase in the number of cases of superior vena cava (SVC) syndrome associated with chronic indwelling central venous catheters. Fibrinolytic therapy and endovascular treatment are currently achieving good results. We present a case history of a patient with SVC with a catheter used for chemotherapy, which was successfully treated with catheter-directed (intraclot) infusion thrombolytic therapy with urokinase.
Subject(s)
Catheterization, Central Venous/adverse effects , Fibrinolytic Agents/therapeutic use , Superior Vena Cava Syndrome/drug therapy , Thrombolytic Therapy/methods , Urokinase-Type Plasminogen Activator/therapeutic use , Anticoagulants/administration & dosage , Anticoagulants/therapeutic use , Antineoplastic Agents/administration & dosage , Antineoplastic Agents/therapeutic use , Breast Neoplasms/drug therapy , Breast Neoplasms/radiotherapy , Breast Neoplasms/surgery , Chemotherapy, Adjuvant , Combined Modality Therapy , Coumarins/administration & dosage , Coumarins/therapeutic use , Drug Therapy, Combination , Female , Fibrinolytic Agents/administration & dosage , Humans , Infusions, Intravenous , Mastectomy, Segmental , Methylprednisolone/therapeutic use , Middle Aged , Radiotherapy, Adjuvant , Subclavian Vein , Superior Vena Cava Syndrome/diagnosis , Superior Vena Cava Syndrome/etiology , Urokinase-Type Plasminogen Activator/administration & dosageABSTRACT
Recently, there has been an increase in the number of cases of superior vena cava (SVC) syndrome associated with chronic indwelling central venous catheters. Fibrinolytic therapy and endovascular treatment are currently achieving good results. We present a case history of a patient with SVC with a catheter used for chemotherapy, which was successfully treated with catheter-directed (intraclot) infusion thrombolytic therapy with urokinase (AU)
