ABSTRACT
UNLABELLED: The authors determine whether or not nurses should use perfusion pumps for concentrated hematin transfusions, measuring the degree of hemolysis which occurs in two distinct models. STUDY SAMPLE: Concentrated hematin transfusions by means of an infusion pump on children in a Pediatrics Intensive Care Unit at the Maternity-Pediatrics Ward in Granada. Dependent Variable: Degree of Hemolysis, measured by means of: free hemoglobin, potassium, LDH. INDEPENDENT VARIABLES: Pump; dated/used blood; hematocrit; catheter caliber; type of procedure; pump working pressure; other perfusion rhythms; infusion rhythm. Sample size. One year study group, 95% confidence rate, 0.50 prevalence of awaited hemolysis, +/- 0.05 precision (relative precision 10%). Data Obtained: Two samples are taken per transfusion: removal of blood bag, extreme distal removal system. Investigative Method: Prospective descriptive study. STATISTICAL ANALYSIS: Descriptive statistics, by means of frequency distributions. Variable analysis, multiple variable analysis. RESULTS: 55 observations were carried, of these, 50.9% corresponded to pump number one. Simple regression linear analysis showed differences in the degree of hemolysis in terms of free hemoglobin and hematocrit. Dated/used blood registered a higher hemolysis level above 75 percentile. The greater hemolysis in terms of potassium difference was associated with the type of procedure, having an average of 0.44 mEq/l, in presence of other perfusions, greater rhythm (p = 0.118), dated/used blood (p = 0.008), hematocrit (p = 0.063). The greatest difference in LDH occurred with smaller caliber catheters, other perfusions, more dated blood (p = 0.117). In multiple linear regression, results were equal to those predicted: an average difference in hemoglobin of 3.87 mg/l (p = 0.661); in potassium, 0.39 mEq/l (p = 0.138); in LDH, 53.6 (p = 0.568). This documents with verify this study have been consulted by the ROL Editorial Board and may be requested from the authors.
