Subject(s)
COVID-19/mortality , Immunosuppressive Agents/therapeutic use , Aged , Female , Hospitalization , Hospitals , Humans , Male , Middle Aged , Risk Factors , SpainABSTRACT
Acrylates are molecules that are well known for their strong sensitizing properties. Historically, many beauticians and individuals using store-bought artificial nail products have developed allergic contact dermatitis from acrylates. More recently, the use of acrylic nails among flamenco guitarists to strengthen their nails has become very popular. A 40-year-old non-atopic male patient working as a flamenco guitarist developed dystrophy, onycholysis and paronychia involving the first four nails of his right hand. The lesions were confined to the fingers where acrylic materials were used in order to strengthen his nails to play the guitar. He noticed improvement whenever he stopped using these materials and intense itching and worsening when he began reusing them. Patch tests were performed and positive results obtained with 2-hydroxyethyl methacrylate (2-HEMA), 2-hydroxyethyl acrylate (2-HEA), ethyleneglycol-dimethacrylate (EGDMA) and 2-hydroxypropyl methacrylate (2-HPMA). The patient was diagnosed with occupational allergic contact dermatitis likely caused by acrylic nails. Artificial nails can contain many kinds of acrylic monomers but most cases of contact dermatitis are induced by 2-HEMA, 2-HPMA and EGDMA. This is the first reported case of occupational allergic contact dermatitis from acrylates in artificial nails in a professional flamenco guitar player. Since the practice of self-applying acrylic nail products is becoming very popular within flamenco musicians, we believe that dermatology and occupational medicine specialists should be made aware of the potentially increasing risk of sensitization from acrylates in this setting.
Subject(s)
Acrylic Resins/adverse effects , Dermatitis, Allergic Contact/etiology , Occupational Exposure/adverse effects , Acrylates/adverse effects , Acrylic Resins/therapeutic use , Adult , Chemical Safety/standards , Chemical Safety/statistics & numerical data , Humans , Male , Methacrylates/adverse effects , Music/psychology , Nails , Occupational Exposure/statistics & numerical dataABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Mohs Surgery/methods , Carcinoma, Skin Appendage/diagnosis , Carcinoma, Skin Appendage/surgery , Carcinoma, Ductal/diagnosis , Carcinoma, Ductal/surgery , Surgical Flaps/surgery , Diagnosis, DifferentialSubject(s)
Mohs Surgery , Skin Neoplasms/surgery , Sweat Gland Neoplasms/surgery , Adult , Humans , MaleABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Dermatitis, Allergic Contact/etiology , 5-Aminolevulinate Synthetase/adverse effects , Darier Disease/drug therapy , Transdermal Patch/adverse effectsABSTRACT
Los efectos adversos cutáneos del tratamiento con interferón alfa o la combinación de interferón alfa y ribavirina en pacientes con hepatitis crónica C son relativamente frecuentes, pero son principalmente locales y relacionados con el lugar de inyección del interferón. Sin embargo, las reacciones eczematosas a distancia o generalizadas son raras. La introducción de los interferones alfa pegilados podría aumentar la frecuencia de estas lesiones cutáneas (AU)
Treatment with interferon alpha or interferon alpha plus ribavirin in patients with chronic hepatitis C frequenty cause cutaneous local side effects limited to the injection sites. Distant or generalized eczematous reactions are rare. However, distant lesions may increase with the use of pegylated interferons alpha (AU)
Subject(s)
Humans , Male , Female , Middle Aged , Eczema/chemically induced , Interferon-alpha/adverse effects , Ribavirin/adverse effects , Hepatitis C, Chronic/drug therapy , Drug Hypersensitivity/complicationsABSTRACT
Las metástasis cutáneas son poco frecuentes y en ocasiones representa la primera manifestación de una neoplasia desconocida. Aunque la clínica esvariable, generalmente se confunde con un proceso infeccioso o inflamatorio. Las metástasis de localización acral son particularmente raras y el pronósticoes muy malo. Presentamos el caso de un paciente con metástasis en las manos y los pies como signo inicial de una neoplasia no conocida previamente (AU)
Cutaneous metastases are infrequent and in some cases represent the first sign of cancer from an unknown primary site. Although the clinical presentationvaries, they are generally confused with an infectious or inflammatory process. Acral metastases are particularly rare and the prognosis is verypoor. A patient with metastases on the hands and feet as an initial sign of a previously unknown tumour is reported (AU)
Subject(s)
Humans , Female , Aged, 80 and over , Endometrial Neoplasms/pathology , Skin Neoplasms/secondary , Adenocarcinoma/pathology , Fatal OutcomeABSTRACT
El fibroxantoma atípico es un tumor infrecuente, de histogénesis incierta. La mayoría de los autores lo consideran una variante superficial del histiocitomafibroso maligno. Generalmente se manifiesta como un nódulo solitario en personas de edad avanzada y zonas expuestas al sol. El diagnósticodel fiborxantoma atípico es siempre de exclusión, y debe diferenciarse mediante inmunohistoquímica de otros tumores fusocelulares como los carcinomas escamosos y melanomas. Describimos las características clínicopatológicas e inmunohistoquímicas de diez casos de fibroxantoma atípico (AU)
Atypical fibroxanthoma is a rare tumor of unknown histogenesis, considered by most authors to represent a superficial or minimally invasive variant ofmalignant fibrous histiocytoma that most often presents as a solitary nodule on sun-exposed skin of the elderly. The diagnosis of atypical fibroxanthomais always one of exclusion. Other spindle-cell tumor such as squamous cell carcinoma and melanoma must be ruled out by immunohistochemical techniques. We report the clinicopathological and immunohistochemical features of ten cases of atypical fibroxanthoma (AU)
Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Skin Neoplasms/diagnosis , Histiocytoma, Malignant Fibrous/diagnosis , Skin Neoplasms/pathology , Diagnosis, Differential , Histiocytoma, Malignant Fibrous/pathology , Histiocytoma, Malignant Fibrous/surgeryABSTRACT
Los efectos adversos cutáneos del tratamiento con interferón alfa o la combinación de interferón alfa y ribavirina en pacientes con hepatitis crónica C son relativamente frecuentes, pero son principalmente locales y relacionados con el lugar de inyección del interferón. Sin embargo, las reacciones eczematosas a distancia o generalizadas son raras. La introducción de los interferones alfa pegilados podría aumentar la frecuencia de estas lesionescutáneas (AU)
Treatment with interferon alpha or interferon alpha plus ribavirin in patientes with chronic hepatitis C frequently cause cutaneous local side effects limited to the injection sites. Generalized eczematous reactions are rare. However, distant lesions may increase with the use of pegylated inteferons alpha (AU)
Subject(s)
Humans , Male , Female , Middle Aged , Interferon-alpha/adverse effects , Eczema/chemically induced , Ribavirin/adverse effects , Hepatitis C, Chronic/complications , Hepatitis C, Chronic/drug therapyABSTRACT
No disponible
Subject(s)
Pregnancy , Adult , Female , Humans , Paresis , Pseudoxanthoma Elasticum , Pregnancy Complications , Angioid Streaks , Cognition DisordersABSTRACT
Presentamos el caso de una familia afectada por leiomiomatosis cutaneouterina familiar o síndrome de Reed. Este proceso asocia leiomiomas múltiples familiares cutáneos y/o uterinos. Es importante su conocimiento tanto por parte del dermatólogo como del ginecólogo. Su diagnóstico obliga a realizar un examen dermatológico a los miembros de la familia afectada, así como controles ginecológicos periódicos a las mujeres de la misma (AU)
