ABSTRACT
Bacille Calmette-Guérin (BCG) administration for superficial bladder cancer is a well-tolerated and very effective therapy. However, unpredictable systemic complications may occur on rare occasions. We present the case of a patient who attended for consultation because of fever, asthenia and weight loss following BCG immunotherapy. The clinical response to treatment and computed tomography scanning were key to diagnosis. LEARNING POINTS: It is essential to keep a high index of suspicion of possible, although uncommon, complications in patients treated with BCG immunotherapy.Response to treatment should always be evaluated to confirm diagnostic suspicion.
ABSTRACT
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Subject(s)
Humans , Male , Middle Aged , Peritonitis/microbiology , Sphingomonas/pathogenicity , Liver Cirrhosis, Alcoholic/complications , Ceftriaxone/therapeutic useABSTRACT
Streptococcus constellatus is a commensal microorganism in man but may cause infections in different locations. We report a 59 years old male with severe sequelae of a previous cerebrovascular accident that consulted in the emergency room for fever of 15 days of evolution. A right empyema was diagnosed. The bacteriological culture of the effusion disclosed the presence of Streptococcus constellatus and two anaerobic strains (Prevotella intermedia and Fusobacterium urealyticus). The patient was treated with a pleural drainage and received ceftriaxone and clindamycin during six weeks. He was discharged in good conditions and is asymptomatic after eight months of follow up.
Subject(s)
Empyema, Pleural/microbiology , Streptococcal Infections/complications , Streptococcus constellatus , Drainage , Empyema, Pleural/therapy , Humans , Male , Middle Aged , Streptococcal Infections/therapy , Stroke/complicationsABSTRACT
Streptococcus constellatus is a commensal microorganism in man but may cause infections in different locations. We report a 59 years old male with severe sequelae of a previous cerebrovascular accident that consulted in the emergency room for fever of 15 days of evolution. A right empyema was diagnosed. The bacteriological culture of the effusion disclosed the presence of Streptococcus constellatus and two anaerobic strains (Prevotella intermedia and Fusobacterium urealyticus). The patient was treated with a pleural drainage and received ceftriaxone and clindamycin during six weeks. He was discharged in good conditions and is asymptomatic after eight months of follow up.
Subject(s)
Humans , Male , Middle Aged , Empyema, Pleural/microbiology , Streptococcal Infections/complications , Streptococcus constellatus , Drainage , Empyema, Pleural/therapy , Streptococcal Infections/therapy , Stroke/complicationsABSTRACT
BACKGROUND: Atrial fibrillation (AF) is well-known risk factor for cardiac embolic events, especially cerebrovascular events. The association between AF and lipid markers was evaluated. Among all these markers, lipoprotein(a), or (Lp(a), was also investigated. The aim of our study was to evaluate the characteristics of the lipid profile in patients with AF, focusing on Lp(a) levels. MATERIAL/METHODS: One hundred and one patients with AF were included in the study group. We used 101 patients without AF, matched by sex and age with the study group, as the control group. Total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, Lp(a), and the LDL/HDL, COL/LDL, and COL/HDL indexes were measured. The study was performed in Spain with a Caucasian population. RESULTS: Among all the variables included there was statistical difference only between groups in the COL/HDL index, showing a greater value in the group of patients with AF. No difference was found in Lp(a) levels between the groups. CONCLUSIONS: Although some studies have tried to show a possible relationship between AF and high Lp(a) levels, we found no such relationship in our study, although ethnic differences could explain, at least in part, these results in our patients when compared with other ethnic populations.
