ABSTRACT
BACKGROUND: The ovarian hyperstimulation syndrome is a serious complication in patients who undergo controlled ovarian stimulation and for that reason all clinicians who prescribe ovulation inducing agents must be prepared to recognize and manage ovarian hyperstimulation syndrome, to prevent severe and ocasionally mortal complications. OBJECTIVE: To communicate the experience in the treatment of ovarian hyperstimulation syndrome as a complication in patients who undergo controlled ovarian stimulation. PATIENTS AND METHODS: In the present study seven patients who developed severe ovarian hyperstimulation syndrome were included, and were treated by ultrasound guided paracentesis and self-transfusion of the ascitic fluid. RESULTS: In all patients we observed a clinical improvement immediately after the drainage of ascitic fluid no hematological or infectious disease were observed after the self-transfusion. We observed a reduction in hemoglobin of 20.9% and 22.2% in the hematocrit after paracentesis and self-transfusion, meanwhile we observed an increase of 55.5% in the albumin level. Any patient developed hemodynamic disturbance after paracentesis after drainage of great volume in the paracentesis (mean of 4453.4 mL per patient). CONCLUSIONS: The drainage of ascitis by paracentesis and self-transfusion of the fluid is a good therapeutic option in patients with severe ovarian hyperstimulation syndrome in combination with intravenous fluids and administration of human albumin 25%.
Subject(s)
Ascitic Fluid , Decompression, Surgical , Ovarian Hyperstimulation Syndrome/therapy , Paracentesis/methods , Adult , Biological Therapy , Combined Modality Therapy , Female , Humans , Severity of Illness IndexABSTRACT
OBJECTIVE: To obtain the linear correlation between Doppler flowmetry rates and follicular development and the observed embryo growth in ovarian hyperstimulation cycles in the IVFTE/ICSI results. MATERIAL AND METHODS: A prospective and observational study including 29 patients was carried out. The ovarian reserve was determined--by the ovaries morphometric conditions--as well as basal FSH. These were correlated with pulsatility rates (PR), resistance rates (RR), and the systole/diastole ratio (S/D) and the maximum flow rate (TAmax), using a USG pulse-colour Doppler. All these were correlated to embryo development. Covariance, regression lines and confidence intervals analyses were performed for its statistical determination. RESULTS: A correlation between RR and the formation of mature follicles was observed (p = 0.05), and, at the same time, a negative relationship between FSH and ovarian volume was found. CONCLUSIONS: A series of markers of ovarian reserve have been described, however, none of these is a specific marker when ovum quality is expressed through the administration of ovulation inducers. Considering the data obtained in our study, we can say that Doppler flowmetry rates can indicate follicular expression and the resulting ovum and embryo development.
Subject(s)
Embryo Transfer , Embryo, Mammalian/physiology , Fertilization in Vitro , Ovarian Follicle/blood supply , Ovum/physiology , Adult , Female , Humans , Ovarian Follicle/physiology , Ovulation Induction , Rheology , Ultrasonography, DopplerABSTRACT
BACKGROUND: The association of pregnancy and cancer is a rare event, occurring in less than 1 case per 5,000 pregnancies, and is a cause of maternal mortality in about 5% of cases. CASE: A 33-year-old, Japanese woman presented at the end of pregnancy with clinical manifestations of pneumonia and developed fatal disseminated intravascular coagulation in the postpartum period. The pathologic findings suggested the existence of a primary cancer in the gastrointestinal tract with pulmonary and placental metastases. CONCLUSION: The biologic course of malignancies in pregnancy is complex. In gastrointestinal cancer, normal pregnancy symptoms can mask and delay the diagnosis. As in this patient, very rare presentations are possible.
Subject(s)
Adenomatosis, Pulmonary/diagnosis , Disseminated Intravascular Coagulation/complications , Gastrointestinal Neoplasms/diagnosis , Lung Neoplasms/diagnosis , Pregnancy Complications, Neoplastic/diagnosis , Acute Disease , Adenomatosis, Pulmonary/complications , Adenomatosis, Pulmonary/secondary , Adult , Fatal Outcome , Female , Gastrointestinal Neoplasms/complications , Gastrointestinal Neoplasms/pathology , Humans , Infant, Newborn , Lung Neoplasms/complications , Lung Neoplasms/secondary , Male , Postpartum Period , Pregnancy , Pregnancy Complications, Neoplastic/pathology , Pregnancy Trimester, ThirdABSTRACT
La tuberculosis genital (TBG) es secundaria a un proceso infeccioso extragenital, principalmente de origen pulmonar, que se manifiesta con la presencia de infertilidad, oligo ó amenorrea y dolor pélvico. Este reporte informa el caso de una mujer con infertilidad primaria de 6 años de evolución y amenorrea de 8 años, con TBG que se sospecho, luego de un examen de histeroscopía con laparoscopía, toma de biopsia dirigida y confirmación del diagnóstico, a través de cultivos y pruebas específicas de Reacción en Cadena de Polimerasa (PCR). El cultivo continua siendo el método más sensible y específico para el diagnóstico de tuberculosis, a pesar de los largos periodos de incubación.Dado la creciente frecuencia de la TBG y las serias implicaciones en el futuro reproductivo de mujeres afectadas, debido a que la mayoría de los casos son diagnosticados de manera tardía, así como por las consecuencias del tratamiento prolongado con drogas antituberculosas (hasta por 6 meses). Este reporte tiene como objetivo subrayar las ventajas y limitaciones de las nuevas modalidades diagnósticas, como la PCR, raramente empleada para el diagnóstico de TBG.
