Subject(s)
Humans , Male , Adult , Darier Disease/diagnosis , Nail Diseases/diagnostic imaging , DermoscopySubject(s)
Humans , Female , Middle Aged , Melanoma/diagnosis , Skin Neoplasms/diagnosis , DermoscopyABSTRACT
La aftosis oral recidivante es una enfermedad inflamatoria crónica de la mucosa oral. Se caracteriza por presentar úlceras dolorosas en la cavidad oral sin que se encuentre una enfermedad subyacente que lo justifique. Ante la aparición de úlceras recidivantes en la mucosa oral habrá que realizar un correcto diagnóstico diferencial y descartar otras causas antes de llegar al diagnóstico de aftosis oral recidivante. Se trata de una enfermedad frecuente; según la población estudiada, se han documentado prevalencias entre el 5 y el 60%. Su patogenia es desconocida, pero se considera multifactorial. El tratamiento no está estandarizado y no es curativo, se pretende disminuir el dolor durante el brote, acortar la duración del mismo y evitar la aparición de nuevas lesiones
Recurrent aphthous stomatitis is a chronic inflammatory disease of the oral mucosa. It is characterized by painful mouth ulcers that cannot be explained by an underlying disease. Recurrent oral mucosal ulcers require a proper differential diagnosis to rule out other possible causes before recurrent aphthous stomatitis is diagnosed. The condition is common, with prevalence rates ranging from 5 to 60% in different series. Its pathogenesis is unknown, but multiple factors are considered to play a part. There are no standardized treatments for this condition and none of the treatments are curative. The goal of any treatment should be to alleviate pain, reduce the duration of ulcers, and prevent recurrence
Subject(s)
Humans , Stomatitis, Aphthous/diagnosis , Stomatitis, Aphthous/etiology , Stomatitis, Aphthous/therapy , Diagnosis, Differential , Risk Factors , RecurrenceABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Coronavirus Infections/drug therapy , Pneumonia, Viral/drug therapy , Severe Acute Respiratory Syndrome/drug therapy , Drug Hypersensitivity/diagnosis , Severe acute respiratory syndrome-related coronavirus/isolation & purification , Pandemics , Coronavirus Infections/complications , Diagnosis, DifferentialSubject(s)
COVID-19 Drug Treatment , Drug Eruptions , Skin Diseases/chemically induced , Humans , RNA, Viral , SARS-CoV-2 , SkinABSTRACT
Recurrent aphthous stomatitis is a chronic inflammatory disease of the oral mucosa. It is characterized by painful mouth ulcers that cannot be explained by an underlying disease. Recurrent oral mucosal ulcers require a proper differential diagnosis to rule out other possible causes before recurrent aphthous stomatitis is diagnosed. The condition is common, with prevalence rates ranging from 5 to 60% in different series. Its pathogenesis is unknown, but multiple factors are considered to play a part. There are no standardized treatments for this condition and none of the treatments are curative. The goal of any treatment should be to alleviate pain, reduce the duration of ulcers, and prevent recurrence.
Subject(s)
Oral Ulcer , Stomatitis, Aphthous , Humans , Mouth Mucosa , Pain , Recurrence , Stomatitis, Aphthous/diagnosisABSTRACT
No disponible
Subject(s)
Humans , Female , Young Adult , Keratoderma, Palmoplantar/diagnosis , Keratoderma, Palmoplantar/drug therapy , Terbinafine/administration & dosage , Antifungal Agents/administration & dosageABSTRACT
El nevo de Spitz es una neoplasia melanocítica de células epitelioides o fusiformes que suele aparecer en la infancia. Su naturaleza es benigna, aunque en ocasiones puede mostrar unas características difíciles de distinguir del melanoma. En las últimas décadas se han clasificado las neoplasias melanocíticas spitzoides en 3tipos: nevus de Spitz, tumor de Spitz atípico y melanoma spitzoide. El tumor de Spitz atípico hace referencia a las neoplasias melanocíticas spitzoides que tienen unas características histopatológicas atípicas insuficientes para realizar el diagnóstico de melanoma y cuyo potencial maligno, actualmente, es incierto. Nuestro objetivo es revisar los aspectos clínicos, dermatoscópicos, histopatológicos e inmunohistoquímicos de este conjunto de tumores
A Spitz nevus is a melanocytic neoplasm of epithelioid and/or spindle cells that usually appears in childhood. These lesions are by nature benign, but their features can sometimes make them difficult to distinguish from melanomas. Spitzoid melanocytic lesions have been grouped into 3 types in recent decades: Spitz nevi, atypical Spitz tumors, and spitzoid melanomas. Atypical Spitz tumors are spitzoid melanocytic proliferations that have atypical histopathologic features that are insufficient to support a diagnosis of melanoma. The malignant potential of these lesions is at present uncertain. This review examines the clinical, dermoscopic, and histopathologic features of this group of lesions
Subject(s)
Humans , Child , Nevus, Epithelioid and Spindle Cell/diagnosis , Nevus, Epithelioid and Spindle Cell/pathology , Skin Neoplasms/diagnosis , Melanoma/diagnosis , Nevus, Spindle Cell/diagnosis , Immunohistochemistry , Nevus, Epithelioid and Spindle Cell/epidemiology , Skin Neoplasms/pathology , Nevus, Spindle Cell/pathologyABSTRACT
Las neoplasias melanocíticas con morfología spitzoide (nevo de Spitz, tumor de Spitz atípico y melanoma spitzoide) abarcan un espectro desde lesiones benignas a malignas. Debido al potencial maligno incierto de los tumores de Spitz atípicos, el abordaje terapéutico ha generado durante años controversia. El desarrollo de nuevas técnicas moleculares parece prometedor y ha contribuido a una mejor predicción del comportamiento biológico de los tumores de Spitz. Nuestro objetivo es revisar las características citogenéticas de los tumores de Spitz, el pronóstico y actualizar las últimas recomendaciones de manejo
Melanocytic neoplasms with spitzoid morphology (Spitz nevi, atypical Spitz tumors, and spitzoid melanomas) may be benign or malignant. Because the malignant potential of atypical Spitz tumors is uncertain, the proper therapeutic approach has been much debated over the years. Promising new techniques for molecular analysis have enabled better predictions of the biological behavior of these tumors. We review their cytogenetic features and prognosis and also provide an update of the most recent recommendations for management
Subject(s)
Humans , Child , Nevus, Epithelioid and Spindle Cell/diagnosis , Nevus, Epithelioid and Spindle Cell/genetics , Cytogenetics/methods , Prognosis , Melanoma/diagnosis , Nevus, Epithelioid and Spindle Cell/therapy , Melanoma/genetics , Case-Control Studies , CytogeneticsABSTRACT
Melanocytic neoplasms with spitzoid morphology (Spitz nevi, atypical Spitz tumors, and spitzoid melanomas) may be benign or malignant. Because the malignant potential of atypical Spitz tumors is uncertain, the proper therapeutic approach has been much debated over the years. Promising new techniques for molecular analysis have enabled better predictions of the biological behavior of these tumors. We review their cytogenetic features and prognosis and also provide an update of the most recent recommendations for management.
