ABSTRACT
Kaposi´s sarcoma is a rare tumor associated with human herpes virus 8 (HHV-8) infection. Four main clinical subtypes have been described. This study reports on a form of KS in an HIV negative and immunocompetent middle-aged man. The only remarkable factor is that he has sex with other men. This form of Kaposi´s sarcoma is rare. It occurs more in younger patients than in the classic form, is limited to the skin, and is associated with a good prognosis. The means of transmission of the virus is through saliva in oroanal or orogenital sexual practices. Mechanisms of tumor development are still not well known. Given the possible increased number of this variant, it would be interesting to extend this study.
Subject(s)
Immunocompetence , Sarcoma, Kaposi/pathology , Skin Neoplasms/pathology , Herpesvirus 8, Human , Humans , Immunohistochemistry , Male , Middle Aged , Sarcoma, Kaposi/immunology , Skin Neoplasms/immunologyABSTRACT
Abstract: Kaposi´s sarcoma is a rare tumor associated with human herpes virus 8 (HHV-8) infection. Four main clinical subtypes have been described. This study reports on a form of KS in an HIV negative and immunocompetent middle-aged man. The only remarkable factor is that he has sex with other men. This form of Kaposi´s sarcoma is rare. It occurs more in younger patients than in the classic form, is limited to the skin, and is associated with a good prognosis. The means of transmission of the virus is through saliva in oroanal or orogenital sexual practices. Mechanisms of tumor development are still not well known. Given the possible increased number of this variant, it would be interesting to extend this study.
Subject(s)
Humans , Male , Middle Aged , Sarcoma, Kaposi/pathology , Skin Neoplasms/pathology , Immunocompetence , Sarcoma, Kaposi/immunology , Skin Neoplasms/immunology , Immunohistochemistry , Herpesvirus 8, HumanSubject(s)
Eosinophilia/diagnosis , Folliculitis/diagnosis , Scalp Dermatoses/diagnosis , Skin Diseases, Vesiculobullous/diagnosis , Eosinophilia/pathology , Folliculitis/pathology , Humans , Infant , Infant, Newborn , Male , Recurrence , Scalp Dermatoses/pathology , Skin Diseases, Vesiculobullous/pathologyABSTRACT
Sarcoidosis is a multisystem inflammatory disease characterized by the formation of noncaseating granulomas in various organs and tissues. The majority of patients with systemic sarcoidosis will present with lung and lymph node involvement. In addition, 20% have skin involvement that may be the only manifestation of the disease or may be an important prognostic marker for involvement of other organs. There are multiple forms of presentation of cutaneous sarcoidosis, which may be a true challenge.We report a patient with a one month history of an eruption of skin colored papules. Some were grouped in a symmetrical distribution on the trunk, inner arms, and lumbar region. Pathologic examination revealed an infiltrate in the papillary dermis showing a band of noncaseating granulomas along with disruption of the basal lamina and lichenoid changes. The clinicopathological correlation confirmed the diagnosis of lichenoid sarcoidosis. We consider our case interesting owing to the clinical presentation and the lichenoid distribution of granulomas.
