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4.
Rev. esp. patol ; 33(2): 147-151, abr. 2000. ilus
Article in Es | IBECS | ID: ibc-7400

ABSTRACT

El carcinoma basocelular de células granulares es un subtipo de carcinoma basocelular caracterizado por la presencia de células neoplásicas con hallazgos citológicos de células granulares, que forman parte o constituyen la totalidad de la tumoración. Es una variante rara, y el caso que presentamos es el octavo descrito en la literatura mundial. Los estudios inmunohistoquímico y ultraestructural demuestran que las células granulares proliferantes son de origen epitelial (AU)


Subject(s)
Male , Middle Aged , Humans , Carcinoma, Basal Cell/diagnosis , Carcinoma, Basal Cell/etiology , Carcinoma, Basal Cell/pathology , Immunohistochemistry/methods , Microscopy/methods , Carcinoma , Lysosomes/pathology , Phagosomes/pathology , Granular Cell Tumor/diagnosis , Granular Cell Tumor/pathology , Neoplasms, Glandular and Epithelial/diagnosis , Neoplasms, Glandular and Epithelial/pathology , Desmosomes/pathology , Neoplasms, Muscle Tissue/pathology , Neoplasms, Muscle Tissue/diagnosis , Keratins/analysis , Keratins , Stromal Cells/cytology , Stromal Cells/pathology
6.
Rev Esp Enferm Dig ; 88(3): 213-6, 1996 Mar.
Article in Spanish | MEDLINE | ID: mdl-8645516

ABSTRACT

UNLABELLED: Porphyria cutanea tarda (PCT) is caused by reduced activity of hepatic uroporphyrinogen decarboxylase. However extrinsic factors such as alcohol abuse and drug intake are required for the clinical manifestation of the disease. Hepatitis C virus antibodies have been detected in a high percentage of patients with PCT. Hepatitis C virus is probably the main pathogenetic factor of liver damage in patients with PCT. AIM: To study the association between hepatitis C virus and PCT in our patients with PCT. MATERIAL AND METHODS: We have investigated six patients diagnosed of PCT in order to detect the presence of hepatitis C virus and other possible causes of the disease. RESULTS: We have found that 66% of our patients had hepatitis C virus antibodies, 50% ethanol abuse, of which 2/3 presented hepatitis C virus antibodies, and one case of HIV.


Subject(s)
Hepacivirus/immunology , Hepatitis C Antibodies/analysis , Hepatitis C/complications , Hepatitis, Chronic/complications , Porphyria Cutanea Tarda/complications , Adult , Alcoholism/complications , Biopsy , Enzyme-Linked Immunosorbent Assay , HIV Seropositivity/complications , Hepacivirus/genetics , Hepacivirus/isolation & purification , Hepatitis C/diagnosis , Hepatitis, Chronic/diagnosis , Humans , Liver/pathology , Male , Middle Aged , Polymerase Chain Reaction , Porphyria Cutanea Tarda/diagnosis , RNA, Viral/analysis
7.
Rev Esp Enferm Dig ; 88(3): 221-2, 1996 Mar.
Article in Spanish | MEDLINE | ID: mdl-8645518

ABSTRACT

Sarcoidosis is a granulomatous disease of unknown origin with a variable clinical presentation. Although involvement of every organ has been described, the pulmonary system is most frequently involved. Isolated extrapulmonary disease is rare. Hepatic manifestations include granulomatous hepatitis and hilar lymphadenopathy. We describe a case of sarcoidosis initially presenting as extrahepatic jaundice.


Subject(s)
Liver Diseases/diagnosis , Pancreatic Neoplasms/diagnosis , Sarcoidosis/diagnosis , Adult , Cholestasis/etiology , Diagnosis, Differential , Female , Humans , Liver Diseases/complications , Sarcoidosis/complications , Tomography, X-Ray Computed
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