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J Small Anim Pract ; 56(7): 450-5, 2015 Jul.
Article in English | MEDLINE | ID: mdl-25913545

ABSTRACT

OBJECTIVES: To compare cardiac output measured by oesophageal Doppler and by thermodilution monitoring and to correlate the Doppler cardiac output-generated minute distance with thermodilution cardiac output in healthy anaesthetised beagle dogs. MATERIALS AND METHODS: Prospective experimental study. Six healthy adult beagle dogs were pre-medicated with intramuscular acepromazine (0 · 05 mg/kg) and methadone (0 · 3 mg/kg). Anaesthesia was induced with intravenous propofol (dose-effect) and maintained with isoflurane in oxygen. Simultaneously, a constant rate infusion of dopamine (3 µg/kg/minute) was administered to the dogs to prevent hypotension. The minute distance, Doppler and thermodilution cardiac outputs were assessed at three different end-tidal concentrations of isoflurane (1 · 0, 1 · 3 and 2 · 0%). RESULTS: Correlation between Doppler and thermodilution cardiac output (r(2) = 0 · 582) and between minute distance and thermodilution cardiac output (r(2) = 0 · 658) were moderately good, but the limits of agreement between Doppler and thermodilution cardiac outputs were above the recommended values (±39%, for a recommended value up to 30%). CLINICAL SIGNIFICANCE: Doppler and minute distance cannot be considered as an alternative method to thermodilution to monitor cardiac output in the healthy anaesthetised dog.


Subject(s)
Anesthesia, General/veterinary , Cardiac Output/physiology , Dogs/physiology , Monitoring, Intraoperative/veterinary , Animals , Blood Pressure , Echocardiography, Transesophageal/veterinary , Heart Rate , Isoflurane/administration & dosage , Male , Monitoring, Intraoperative/instrumentation , Signal Processing, Computer-Assisted/instrumentation , Thermodilution/veterinary
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