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1.
Angiología ; 65(6): 211-217, nov.-dic. 2013. tab, graf
Article in Spanish | IBECS | ID: ibc-117088

ABSTRACT

Objetivo: Analizar los efectos del clampaje suprarrenal (CSR) frente al clampaje infrarrenal (CIR) en la evolución de la función renal en la cirugía del aneurisma de aorta abdominal (AAA). Material y método: Estudio de cohortes retrospectivo de los AAA tratados mediante cirugía abierta electiva entre 1998 y 2011. Se analizó la creatinina sérica (mg/dl) preoperatoria y a las 24, 48, 72, 96 h postoperatorias y al alta. Se definió deterioro de la función renal como una creatinina > 2 mg/dl en los pacientes con una creatinina basal normal o un aumento del doble de la creatinina basal en los pacientes con IRC previa. Se definió deterioro del filtrado glomerular (FG) como una disminución > 25%. Análisis multivariable de la evolución de la función renal. Resultados: Se analizaron 464 AAA, 359 (77,4%) con CIR y 105 (22,6%) con CSR. La prevalencia de IRC preoperatoria fue similar entre ambos grupos. El tipo de clampaje no se asoció a deterioro de la función renal (CSR = 8,6% vs. CIR = 4,7%; p = 0,13) y sí al deterioro del FG (CSR = 27,6% vs. CIR = 13,4%; p = 0,001). El tiempo de clampaje, la pérdida sanguínea y la IRC preoperatoria fueron factores de riesgo independientes para deterioro de la función renal. El tipo de clampaje aumentó el riesgo de deterioro de la función renal a partir de los 30 min (p = 0,001), asociándose a deterioro del FG (OR 2,04; IC 95% 0,94-4,47) de forma independiente. Conclusión: Con CSR inferiores a 30 min, en pacientes con creatinina normal, no es previsible un deterioro de la función renal. Con IRC previa o si se espera un CSR prolongado, es esperable un deterioro de la función renal, por lo que deberían valorarse métodos de protección renal (AU)


Objective: To analyse the effects of suprarenal cross-clamping (SC) as opposed to the infrarenal position (IC) in the evolution of the renal function abdominal aorta aneurysm (AAA) surgery. Material and method: A retrospective cohort study of AAAs treated by elective open surgery between 1998 and 2011. The preoperative level of serum creatinine (mg/dL) was determined and compared to postoperative level at 24, 48, 72 and 96 hours, and on discharge. A deterioration in the renal function was defined as a creatinine > 2 mg/dL in patients with a normal baseline creatinine level or an increase of double the baseline creatinine in patients with a previous chronic renal insufficiency (CRI). A deterioration of the glomerular filtrate (GF) was defined as a > 25% decrease. Multivariable analysis was performed on the evolution of the renal function. Results: A total of 464 AAA’s were analysed, 359 (77.4%) with IC, and 105 (22.6%) with SC. The prevalence of preoperative CRI was similar in both groups. The type of clamp was not associated with a deterioration in the renal function (SC = 8.6% vs. IC = 5.7%; p = 0.13) but was associated with a deterioration of the GF (SC = 27.6% vs. IC = 13.4%; p = 0.001). The time the clamp was in place, the blood loss, and the preoperative CRI were independent risk factors for the deterioration of the renal function. The type of clamp increased the risk of deterioration of the renal function beyond 30 minutes (p = .001), being independently associated with a deterioration in the GF (OR 2.04; 95% CI: 0.94-4.47). Conclusion: With SC less than 30 min, in patients with a creatinine level, a deterioration in the renal function is not foreseeable. With prior CRI, or if a prolonged SC is foreseen, a deterioration in the renal function can be expected, thereby making it necessary to evaluate methods for renal protection (AU)


Subject(s)
Humans , Aortic Aneurysm, Abdominal/surgery , Glomerular Filtration Rate , Constriction , Juxtaglomerular Apparatus , Kidney Function Tests , Retrospective Studies , Postoperative Complications/epidemiology
3.
Angiología ; 64(5): 206-211, sept.-oct. 2012. tab, graf, ilus
Article in Spanish | IBECS | ID: ibc-102627

ABSTRACT

Objetivos: Presentar los resultados del tratamiento quirúrgico electivo de los aneurismas inflamatorios de aorta abdominal (AIAA) y analizar la evolución de la inflamación periaórtica (IPA) y de los reactantes de fase aguda (RFA) tras la intervención. Material y método: Se ha realizado un análisis retrospectivo de los AIAA intervenidos de forma electiva entre 1990 y 2010 mediante cirugía abierta. El seguimiento mediano ha sido de 71 meses y se ha analizado la evolución de la IPA y de los RFA tras la intervención. Resultados: Se han tratado 38 pacientes, de los cuales 12 (31,5%) eran sintomáticos. Se evidenció hidronefrosis en 7 casos (18,4%), siendo necesaria la colocación de doble-J preoperatorio en 5 (13,1%). Un paciente (2,6%) falleció en el postoperatorio inmediato y se realizaron 3 reintervenciones por sangrado (7,8%). Durante el seguimiento la hidronefrosis mejoró en 5 pacientes (71%), siendo la supervivencia a los 12, 36 y 72 meses del 92, 85 y 81% respectivamente. En cuanto a los RFA, se produjo una reducción significativa tanto de la velocidad de sedimentación globular (VSG) (p 0,01), como de la proteína C reactiva (PCR) (p 0,01) tras la cirugía. De igual forma, se redujo de forma significativa la IPA durante el seguimiento, fundamentalmente a partir de los 9 meses tras la intervención (p 0,02). Conclusiones: La cirugía electiva del AIAA ofrece unos buenos resultados a corto y largo plazo, asociándose a una disminución de los RFA y de la IPA, esta última fundamentalmente a partir del noveno mes postoperatorio(AU)


Objectives: To show the results of selective surgical treatment of inflammatory abdominal aortic aneurysms (IAAA), and to analyse the evolution of periaortic inflammation (PAI) and acute phase reactants (APR) after surgery. Patients and method: A retrospective analysis was made of the IAAA electively operated on between 1990 and 2010 by means of open surgery. The median follow-up period was 71 months and an analysis was made of the PAI and APR after surgery. Results: A total 38 patients underwent treatment, of which 12 (31.5%) were symptomatic. Hydronephrosis was evident in 7 cases (18.4%). The implantation of a pre-operative double-J catheter was necessary in 5 cases (13.1%). One patient (2.6%) died in the immediate post-operative period, and 3 were re-operated on due to bleeding (7.8%). During the follow-up period the hydronephrosis improved in 5 patients (71%), with a survival rate at 12, 36 and 72 months of 92%, 85% and 81%, respectively. With regard to the APR, a significant reduction was produced both in the erythrocyte sedimentation rate (ESR) (P=.01) and in the C-reactive protein (CRP) (P=.01) after surgery. Likewise, the PAI was significantly reduced during the follow-up period, mainly from the ninth month following the surgery (P=.02). Conclusions: Selective surgery of IAAA offers good results in the short and long term, associated with a decrease in the APR and PAI, the latter mainly from the ninth month of the post-operative period(AU)


Subject(s)
Humans , Aortic Aneurysm, Abdominal/surgery , Acute-Phase Proteins/analysis , Inflammation Mediators/analysis , Inflammation/physiopathology , Hydronephrosis/physiopathology
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