ABSTRACT
Bilateral lesions of the nuclei prepositus hypoglossi produced a more than twofold decrease in the mean frequency discharges in the neurons of the nucleus coeruleus. The number of neurons with burst activity and the number of polymodal neurons substantially increased. Lesion of the nucleus tractus solitarius resulted in an increase in the number of neurons with regular activity and certain decrease in the mean discharge frequency of coeruleus neurons. The results confirm the suggestion about a substantial role of the nucleus prepositus hypoglossi in relaying afferent effects to the activity of locus coeruleus neurons.
Subject(s)
Locus Coeruleus/physiopathology , Medulla Oblongata/pathology , Neurons, Afferent/physiology , Neurons, Efferent/physiology , Animals , Electric Stimulation/instrumentation , Hypoglossal Nerve/physiopathology , Microelectrodes , Rats , Solitary Nucleus/pathology , Time FactorsABSTRACT
The article deals with the comparative characteristics of the changes in immunological indices in 40 patients with non-specific purulent diseases of the lungs and pleura when plasmapheresis and hemosorption were included in the complex of therapeutic measures. The changes were found to be hetero-directional in character: a non-specific effect of immunostimulation in hemosorption, and immunodepression, particularly marked in the first 24 hours, in plasmapheresis. The post-aggressive reaction after plasmapheresis is either absent or delayed significantly, which makes it possible to conduct detoxification in extremely grave conditions of the patients without making the mechanisms of the post-aggressive reaction operative, as observed in performance of hemosorption.
Subject(s)
Empyema, Pleural/immunology , Empyema, Pleural/therapy , Hemoperfusion , Lung Abscess/immunology , Lung Abscess/therapy , Plasmapheresis , Gangrene , Humans , Lung/immunology , Lung/pathology , Suppuration , Time FactorsABSTRACT
The article describes the method of drug pleurodesis and determines the indications for its application. Study of the late-term results and the drawn conclusions provide evidence that the method of drug pleurodesis may de an alternative to operative treatment of spontaneous pneumothorax.