ABSTRACT
More studies evaluating the outcome of dental implant restorations in diabetics are needed. To investigate the outcome of immediate function implant rehabilitations in diabetic patients. This retrospective cohort study included 70 diabetic patients (type 1 = six patients; type 2 = 64 patients; 33 females and 37 males, mean age=59 years), rehabilitated with 352 implants. Primary outcome measure was implant survival estimated at 5 years through the Kaplan-Meier product limit estimator using the patient as unit of analysis (first implant failure as reference); secondary outcome measures were marginal bone loss and biological complications. Risk indicators associated with bone loss >2·0 mm were tested in a multivariate logistic regression model. The level of significance considered was 5%. Seven patients were lost to follow-up (10%). Seven patients lost ten implants rendering a global implant cumulative survival rate for diabetic patients of 89·8% (type 1 = 80·0%; type 2 = 90·5%). The average (95% confidence interval) marginal bone loss at 1 and 5 years was 1·64 mm (0·00;3·32) and 2·55 mm (1·38;3·72) for type 1 diabetic patients, 0·79 mm (0·59;1·00) and 1·45 mm (1·09;1·82) for type 2 diabetic patients and 0·88 mm (0·65;1·10) and 1·56 mm (1·21;1·91) overall. Biological complications occurred in seven patients. Female gender (OR = 28·1) and smoking habits (OR = 10·3) were risk indicators for marginal bone loss >2·0 mm at 5 years when controlled for other variables of interest. Implant rehabilitations represent a valid treatment for diabetic patients, with a good risk/benefit ratio. Female gender and smoking habits were risk indicators for a higher marginal bone resorption at 5 years.
Subject(s)
Alveolar Bone Loss/prevention & control , Dental Implants , Dental Prosthesis, Implant-Supported , Diabetes Complications/prevention & control , Diabetes Mellitus/surgery , Adult , Aged , Aged, 80 and over , Alveolar Bone Loss/physiopathology , Blood Glucose , Diabetes Mellitus/physiopathology , Female , Humans , Male , Middle Aged , Portugal/epidemiology , Practice Guidelines as Topic , Retrospective Studies , Risk FactorsABSTRACT
OBJECTIVE: Our objective is to contribute an updated view on a condition as rare as oat-cell carcinoma of the esophagus by reviewing the literature and reporting two recent patients seen in our department. MATERIAL AND METHOD: A retrospective study with a review of all medical records of patients seen in our ward and diagnosed with esophageal neoplasm for 6 years (January 2000 to December 2006). RESULTS: 249 cases of esophageal neoplasms were found, of them 106 were of squamous ancestry (42.6%), 141 were adenocarcinomas (56.6%), and 2 were oat-cell carcinomas (0.8%). Only in 45 (18%) was surgical resection feasible, 23 underwent palliative surgery (endoprostheses, gastrostomies, and jejunostomies not included) (9.3%), and the rest (181 cases, 72.7%) received derivative surgery or no surgery at all. CONCLUSIONS: We can affirm that this neoplasm is highly aggressive, displaying in practically all cases dissemination to other sites; this is a rare cancer that mainly affects men and whose clinical picture is similar to that of other malignancies involving the esophagus.
Subject(s)
Carcinoma, Small Cell , Esophageal Neoplasms , Aged , Carcinoma, Small Cell/diagnosis , Carcinoma, Small Cell/therapy , Esophageal Neoplasms/diagnosis , Esophageal Neoplasms/therapy , Female , Humans , Male , Retrospective StudiesABSTRACT
Objetivo: nuestro objetivo es aportar una visión actualizadasobre una patología tan infrecuente como el carcinoma oat-cellesofágico, mediante revisión de la bibliografía y la exposición dedos casos de reciente aparición en nuestro servicio.Material y método: se realizó un estudio retrospectivo conrevisión de las historias clínicas de los pacientes ingresados ennuestro servicio con el diagnóstico de neoplasia esofágica en losúltimos 6 años (enero de 2000 a diciembre de 2006).Resultados: se estudiaron 249 casos de neoplasias de esófagoen el curso de este periodo de 6 años, de ellas 106 fueron deestirpe epidermoide (42,6%), 141 adenocarcinomas (56,6%) y 2oat-cell (0,8%). Del total de estos tumores sólo en 45 (18%) deellos se pudo realizar resección quirúrgica, en 23 (9,3%) cirugíapaliativa (no se incluyen prótesis endoscópicas, gastrostomías niyeyunostomías) y en el resto (181 casos, 72,7%) cirugía derivativao ninguna opción quirúrgica.Conclusiones: podemos afirmar que esta neoplasia es altamenteagresiva, presentando en prácticamente la totalidad de los casosdiseminación a otras localizaciones. Se trata de un cáncer muy pocofrecuente que afecta mayoritariamente a varones y cuya clínica es similaral resto de procesos neoplásicos que afectan al esófago
Objective: our objective is to contribute an updated view on acondition as rare as oat-cell carcinoma of the esophagus by reviewingthe literature and reporting two recent patients seen in our department.Material and method: a retrospective study with a review ofall medical records of patients seen in our ward and diagnosed withesophageal neoplasm for 6 years (January 2000 to December2006).Results: 249 cases of esophageal neoplasms were found, ofthem 106 were of squamous ancestry (42.6%), 141 were adenocarcinomas(56.6%), and 2 were oat-cell carcinomas (0.8%). Onlyin 45 (18%) was surgical resection feasible, 23 underwent palliativesurgery (endoprostheses, gastrostomies, and jejunostomies not included)(9.3%), and the rest (181 cases, 72.7%) received derivativesurgery or no surgery at all.Conclusions: we can affirm that this neoplasm is highly aggressive,displaying in practically all cases dissemination to othersites; this is a rare cancer that mainly affects men and whose clinicalpicture is similar to that of other malignancies involving theesophagus
Subject(s)
Male , Female , Aged , Humans , Esophageal Neoplasms/pathology , Retrospective Studies , Carcinoma, Small Cell/pathology , Neoplasm Metastasis/pathologySubject(s)
Osteoma, Osteoid , Ribs , Thoracic Neoplasms , Adult , Female , Humans , Osteoma, Osteoid/pathology , Ribs/pathology , Thoracic Neoplasms/pathologyABSTRACT
Results in a series of 30 dogs subjected to tracheal resection and repair are described. The dogs were divided into three groups. Seven to ten rings of the trachea were resected and then were replaced by a prosthesis made of dura mater and stainless steel wire. Different aspects of the procedures for respiratory support in the three groups are evaluated, as are the different kinds of prostheses used. Our results with ventilatory studies showed taht the mose effective means of respiratory support was insertion of an endotracheal tube after thoracotomy. Among the prostheses, the one used in the third group of dogs, a stainless steel spring covered with only one layer of dura mater, allowed a longer survival period but eventually caused late scarring and stenosis.
