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Medication dosing errors in hospitalized patients with renal impairment: a study in Palestine.

Sweileh, Waleed M; Janem, Samah A; Sawalha, Ansam F; Abu-Taha, Adham S; Zyoud, Sa'ed H; Sabri, Iyad A; Al-Jabi, Samah W; Jaradat, Nidal A; Zaid, Abed Al-Naser M.

Pharmacoepidemiol Drug Saf ; 16(8): 908-12, 2007 Aug.

Article in English | MEDLINE | ID: mdl-17464934

ABSTRACT

BACKGROUND AND AIM: Reduced renal function requires dose adjustment for certain drugs to avoid toxicity. The aim of this study was to determine whether appropriate dosage adjustments were made for drugs that are nephrotoxic, excreted, or metabolized (TEM medications) by the kidney in patients with renal impairment. METHODOLOGY: A cross-sectional study of a group of hospitalized patients was carried out at Al-Watni governmental hospital, Nablus, Palestine. All patients with creatinine clearance

Subject(s)

Medication Errors , Pharmaceutical Preparations/administration & dosage , Renal Insufficiency/drug therapy , Adult , Aged , Aged, 80 and over , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/adverse effects , Anti-Bacterial Agents/pharmacokinetics , Creatinine/blood , Creatinine/urine , Cross-Sectional Studies , Digoxin/administration & dosage , Digoxin/adverse effects , Digoxin/pharmacokinetics , Drug-Related Side Effects and Adverse Reactions , Female , Hospital Bed Capacity, 100 to 299 , Hospitals, Public , Humans , Israel , Male , Middle Aged , Models, Statistical , Pharmacokinetics , Ranitidine/administration & dosage , Ranitidine/adverse effects , Ranitidine/pharmacokinetics , Renal Insufficiency/physiopathology

ABSTRACT

Subject(s)

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