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J Pediatric Infect Dis Soc ; 9(3): 386-389, 2020 Jul 13.
Article in English | MEDLINE | ID: mdl-31310312

ABSTRACT

We assessed the safety and efficacy of a generic form of ledipasvir-sofosbuvir for the treatment of hepatitis C virus infection in Egyptian adolescents and compared the results with those of treatment with the brand-named form. The generic form resulted in a high response rate, significant improvement in liver function, and mild adverse effects. These results are comparable with those of the brand form at a reduced price.


Subject(s)
Antiviral Agents/therapeutic use , Benzimidazoles/therapeutic use , Fluorenes/therapeutic use , Hepatitis C, Chronic/drug therapy , Uridine Monophosphate/analogs & derivatives , Adolescent , Antiviral Agents/adverse effects , Benzimidazoles/adverse effects , Blood Transfusion , Child , Drug Combinations , Drugs, Generic/adverse effects , Drugs, Generic/therapeutic use , Egypt , Female , Fluorenes/adverse effects , Hepatitis C, Chronic/therapy , Humans , Male , Prospective Studies , Sofosbuvir , Uridine Monophosphate/adverse effects , Uridine Monophosphate/therapeutic use
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