ABSTRACT
Ovarian cancer (OC) is the most lethal gynecological malignancy with majority of cases diagnosed in advanced stages and associated with high morbidity and mortality. Positron emission tomography/computed tomography (PET/CT) has emerged as an integral part of the management of several nongynecological cancers. We used PubMed search engine using MeSH words "ovarian cancer" and "PET/CT" and reviewed the current status of PET/CT in epithelial OC. Its application related to ovarian tumor including adnexal mass evaluation, baseline staging, as a triaging tool for upfront surgery or neoadjuvant chemotherapy, for response assessment and prognostication, and for relapse detection and treatment planning has been highlighted. we highlight the current guidelines and newer upcoming PET modalities and radiotracers.
ABSTRACT
ABSTRACT: Melanomas usually arise in the sun exposed parts of the skin. Mucosal melanoma is a rare condition. Melanoma of glans penis is even a rarer phenomenon with less than 250 cases reported in literature so far. Here we present a case of a 55-year-old man diagnosed with melanoma of glans penis with findings on 18F FDG PET/CT scan done for metastatic workup. 18F-FDG PET/CT showed primary in the glans penis with metastases in the right supraclavicular, mediastinal, and abdominal lymph nodes.
Subject(s)
Fluorodeoxyglucose F18 , Melanoma , Humans , Male , Melanoma/diagnostic imaging , Middle Aged , Penis , Positron Emission Tomography Computed Tomography , RadiopharmaceuticalsABSTRACT
PURPOSE: Female genital Tuberculosis (FGTB) causes infertility and formation of Tubo-ovarian (TO) masses. The study showed treatment response of PET-CT in evaluation of anti-tubercular treatment response in patients of infertility with tuberculous TO masses. METHOD: It's a Prospective study on 47 confirmed cases of FGTB with infertility having TO masses. All patients were subjected to 18F-FDGPET/CT to see the glucose uptake by the TO mass and extent of the disease. Category I treatment under DOTS was given for 6 months. All underwent follow-up of PET/CT to see the response to ATT. Results of pre ATT PET/CT were compared with post ATT PET/CT. RESULTS: TO masses was in 42 (89.36%); bilateral in 18 (38.29%) FDG uptake in 14 (29.78%) and without FDG uptake in 4 (8.51%) cases. Right sided mass in 13 (27.65%) FDG uptake in 9 (19.14%) and without FDG uptake in 4 (8.51%) cases. Left sided mass in 11 (23.40%) FDG uptake in 7 (14.89%) and without FDG uptake in 4 (8.51%) cases. Post ATT, there was significant decrease in most parameters. Repeat PET-CT done in 44 cases showed TO mass in 9 (20.45%); bilateral in 4 (9.09%) (FDG uptake in 2.27%) (p < 0.001), right sided in 3 (6.85%) (FDG uptake in 2.27%) (p < 0.002) and left side in 2 (2.27%) FDG uptake in 1 case (p < 0.004). Pelvic and mesenteric lymphadenopathy without FDG uptake was in 1 case (p value = 0.03) while omental and peritoneal deposits without FDG uptake in 1 and 2 cases, respectively. CONCLUSION: PET-CT is useful in treatment response evaluation of tubercular TO masses.
Subject(s)
Ovarian Neoplasms , Positron Emission Tomography Computed Tomography , Female , Fluorodeoxyglucose F18 , Humans , Positron-Emission Tomography , Prospective Studies , RadiopharmaceuticalsABSTRACT
ABSTRACT: We present the case of a 33-year-old woman with complaints of headache and palpitations with raised urinary catecholamines. Ultrasound of the abdomen was noncontributory, and the patient was referred for 68Ga-DOTANOC PET/CT, which revealed tracer accumulation in the thecal sac/spinal canal at D5-D7 level, suggestive of a thoracic paraganglioma. MRI of the spine subsequently confirmed the presence of an extradural mass in the spinal canal extending from D4 to D8.
Subject(s)
Organometallic Compounds , Paraganglioma , Adult , Female , Humans , Multimodal Imaging , Paraganglioma/diagnostic imaging , Positron Emission Tomography Computed Tomography , Positron-Emission Tomography , Tomography, X-Ray ComputedABSTRACT
We describe the extrastriatal accumulation of dopamine transporter imaging agent Tc-TRODAT in the peri-infarct area in a 75-year-old man referred for dopamine transporter SPECT imaging with a suspicion of idiopathic Parkinson disease.
Subject(s)
Infarction/metabolism , Organotechnetium Compounds/metabolism , Tropanes/metabolism , Aged , Brain/diagnostic imaging , Brain/metabolism , Dopamine Plasma Membrane Transport Proteins/metabolism , Humans , Infarction/complications , Infarction/diagnostic imaging , Male , Parkinson Disease/complications , Tomography, Emission-Computed, Single-PhotonABSTRACT
Rectal carcinoma with metastasis to skeletal muscle is rare. So far, 16 cases of skeletal muscle metastasis from colorectal carcinoma have been documented of which only 5 were rectal carcinomas.[1] We discuss here the case of a 69-year old male, a known case of mucinous adenocarcinoma status post neoadjuvant chemoradiotherapy and abdomino perineal resection, who presented with low backache 4 months post surgery. He was found to have metastasis to multiple skeletal muscles without the involvement of common sites, such as liver and lung. The role of 18-FDG-PET/CT in such cases is rarely reported in the literature. This case highlights the importance of utilizing 18-FDG-PET/CT in detecting sites of skeletal muscle metastasis and thereby guides appropriate management.
