ABSTRACT
Pulmonary hypertension (PH) and its direct sequel, namely progressive arterial hypoxemia, is one of the severe complications of acute severe pneumonia (ASP). The paper presents the view of the pathogenesis of PH in patients with ASP and discusses a treatment for this complication. Based on the results of their own studies, the authors propose one of the effective methods for decreasing pulmonary vascular resistance. This method is based on the vasoconstrictor concept of the pathogenesis of PH in PH and includes therapy with nitrates. The authors propose to use drugs ameliorating pulmonary arterial hypertension, particularly intravenous nitrates in a dose of 0.2-0.3 mg/kg/day, as a part of intensive care.
Subject(s)
Critical Care/methods , Hemodynamics/physiology , Hypertension, Pulmonary/therapy , Pneumonia/therapy , Pulmonary Circulation/physiology , Acute Disease , Adolescent , Adult , Combined Modality Therapy , Humans , Hypertension, Pulmonary/etiology , Hypertension, Pulmonary/physiopathology , Middle Aged , Pneumonia/complications , Pneumonia/physiopathology , Severity of Illness IndexABSTRACT
Search for new methods for the earliest possible diagnosis of pre-eclampsia for timely purposeful correction of the consequences of developing disorders remains the central problem of obstetrics. We evaluated the viability of some organs by measuring specific antibody titers. The study was carried out in healthy women and patients with severe gestosis. Gestosis induced pronounced degenerative processes involving predominantly the liver, kidneys, myocardium, lungs, and ocular retina. This method early detects organ changes in gestosis and thus allows timely specific therapy.
