ABSTRACT
The case of idiopathic orthostatic hypotension (Bradbury-Eggleston syndrome) which gradually arose in 70-years-old women was described. The clinical pattern of syndrome included pronounced orthostatic hypotension, fixed constant rare pulse (46-56 per minutes), independent of the changes in body position together with hypohidrosis and constipation. Autonomic nervous system investigation carried out with the help of the cardiovascular tests, spectral analysis of heart rhythm as well as sympathetic skin potential revealed expressed disturbances in autonomic functions of cardiovascular and sudomotor systems. Peculiarity of the case was the development of disease on the background of drug-compensated hypothyreosis which was not however the cause of progressive autonomic disorders in patient.
Subject(s)
Hypotension, Orthostatic/diagnosis , Aged , Autonomic Nervous System Diseases/complications , Autonomic Nervous System Diseases/diagnosis , Autonomic Nervous System Diseases/therapy , Chronic Disease , Combined Modality Therapy , Female , Humans , Hypotension, Orthostatic/etiology , Hypotension, Orthostatic/therapy , Neurologic Examination , SyndromeABSTRACT
Patients with diffuse toxic goiter and those with vegetative dystonia and paroxysmal permanent disorders are shown to have parasympathetic deficiency and moderate sympathetic insufficiency. In toxic goiter patients hyperhydrosis was accompanied by normal conduction along the vegetative perspiration fibers and a significant increase in foot potential amplitude. In patients having vegetative crises there was reduced conduction along the perspiration fibers. Clinical symptoms of enhanced sympathetic activity in both the diseases can be explained by weak parasympathetic influences and hypersensitivity of peripheral tissues to catecholamines. Spilberger test ascertained high reactive and personal anxiety in both groups. By modified MMPI, toxic goiter patients are characterized by hypochondriac, depressive and anxiety trends. Patients with vegetative crises were prone to demonstrative reactions, hypochondria and anxiety.
Subject(s)
Autonomic Nervous System Diseases/physiopathology , Autonomic Nervous System/physiopathology , Thyrotoxicosis/physiopathology , Adolescent , Adult , Autonomic Nervous System Diseases/diagnosis , Autonomic Nervous System Diseases/psychology , Chronic Disease , Dystonia/diagnosis , Dystonia/physiopathology , Dystonia/psychology , Female , Graves Disease/diagnosis , Graves Disease/physiopathology , Graves Disease/psychology , Humans , Male , Thyrotoxicosis/diagnosis , Thyrotoxicosis/psychologyABSTRACT
Quantitative estimation of the status of the autonomic nervous system is a research priority in neurology. One of the approaches to its solving lies in the use of cardiovascular tests. The authors brief the mechanisms of the tests, provide their standards. Show the characteristic patterns of the cardiovascular tests in different diseases of both organic and psychogenic nature. Taking into consideration the simplicity, accessibility, and noninvasive nature of the tests, it is recommended that the cardiovascular tests may be employed for estimating the status of the autonomic nervous system in a wide range of diseases of both neurological and somatic origin.
Subject(s)
Autonomic Nervous System Diseases/diagnosis , Autonomic Nervous System/physiopathology , Blood Vessels/innervation , Bradycardia/diagnosis , Heart/innervation , Hypotension, Orthostatic/diagnosis , Tachycardia/diagnosis , Autonomic Nervous System Diseases/physiopathology , Blood Pressure/physiology , Blood Vessels/physiopathology , Bradycardia/physiopathology , Heart/physiopathology , Heart Function Tests , Heart Rate/physiology , Humans , Hypotension, Orthostatic/physiopathology , Tachycardia/physiopathologyABSTRACT
The purpose of the study was to examine vegetative innervation of the pupil in different diseases associated and not associated with vegetative disorders. In addition to the ++clinico-neurological method, the main method of examination was to study the pupillary cycle (determination of the time of the pupillary cycle (TPC) with the aid of a slit lamp). Fifty healthy test subjects and 262 patients suffering from different somatic and neurologic diseases were examined. The patients were divided in 9 clinical groups: spinal amyotrophy, neural Charcot-Marie amyotrophy, Guillain-Barre syndrome, diabetes mellitus, thyrotoxicosis, hemicrania, Raynaud's disease, idiopathic hyperhidrosis, vegetative crises. The data obtained demonstrate varying grades of the rise of the TPC in the indicated diseases, which reflects varying degrees of vegetative innervation of the pupil insufficiency. However, no well-defined correlation was obtained between the intensity of the psychovegetative syndrome and the TPC. Therefore, it has been shown that the method of determining the TPC is unsophisticated and noninvasive and can be successfully used in different forms of pathology to identify vegetative insufficiency at different stages of the disease.
