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1.
Soc Psychiatry Psychiatr Epidemiol ; 52(5): 587-593, 2017 05.
Article in English | MEDLINE | ID: mdl-28260128

ABSTRACT

PURPOSE: Aim of the study is to evaluate the predictive power of Expressed Emotion in Schizophrenia relapse in Pakistan. METHOD: A longitudinal study was conducted comprising 53 in-patients' sample diagnosed with Schizophrenia and their 101 key carers. Participants fulfilled DSM-IV-TR criteria for Schizophrenia based on Structural Clinical Interview for the DSM-IV diagnosis. Symptomatic status was measured through Brief Psychiatric Rating Scales-Expanded (BPRS-E). Caregivers' level of EE was assessed through Camberwell Family Interview (CFI). Patients were followed up for 9 months after hospital discharge. RESULTS: Relapse rate for patients with high-EE household was 72% as compared with 36% in the low-EE household. Logistic Regression showed a positive relationship between high-EE and relapse (CI 0.06-0.80; p < 0.05). Both hostility and critical comments emerged as significant predictors of relapse. The odds ratio showed that a one unit increase in caregivers' score on the CCs and hostility scales were associated with a 1.29 (CI 1.06-1.56; p < 0.05) and 1.89 (CI 1.14-3.13; p < 0.05) times increased rate of relapse, respectively. Conversely, a non-significant relationship was observed between EOI and relapse. CONCLUSIONS: The findings from this study confirmed the validity of EE construct in predicting schizophrenia relapse in a Pakistani sample. However, medication compliance has not been experimentally controlled and that is one of the limitations of the study.


Subject(s)
Expressed Emotion , Family/psychology , Inpatients/psychology , Schizophrenic Psychology , Adult , Brief Psychiatric Rating Scale , Caregivers/psychology , Female , Follow-Up Studies , Hostility , Humans , Logistic Models , Longitudinal Studies , Male , Middle Aged , Odds Ratio , Pakistan , Recurrence , Young Adult
2.
Schizophr Res ; 159(2-3): e1-22, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25306204

ABSTRACT

The 4th Schizophrenia International Research Society Conference was held in Florence, Italy, April 5-9, 2014 and this year had as its emphasis, "Fostering Collaboration in Schizophrenia Research". Student travel awardees served as rapporteurs for each oral session, summarized the important contributions of each session and then each report was integrated into a final summary of data discussed at the entire conference by topic. It is hoped that by combining data from different presentations, patterns of interest will emerge and thus lead to new progress for the future. In addition, the following report provides an overview of the conference for those who were present, but could not participate in all sessions, and those who did not have the opportunity to attend, but who would be interested in an update on current investigations ongoing in the field of schizophrenia research.


Subject(s)
Gene-Environment Interaction , International Cooperation , Schizophrenia , Brain/pathology , Humans , Italy , Neuroimaging , Schizophrenia/diagnosis , Schizophrenia/genetics , Schizophrenia/therapy , Societies, Medical
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