Subject(s)
Hemophilia A/psychology , Adolescent , Child , Humans , Male , Personality , Psychology, Adolescent , Psychology, Child , Psychology, SocialABSTRACT
The blood plasma levels of medium-mass molecules (MMM) have been studied by UV spectrophotometry in patients with hemophilia A, B, and AB. The hemocoagulation status has been estimated with the use of the parameters reflecting the general blood coagulation ability and with the correction tests, using the thromboplastin generation test. The MMM levels in all hemophilia forms under study have been found essentially elevated vs. those in health. A clear-cut relationship between the severity of hemostasis disorders, blood plasma MMM levels, and the coagulologic parameters has been demonstrated.
Subject(s)
Blood Coagulation Disorders/blood , Hemophilia A/blood , Adolescent , Adult , Humans , Middle Aged , Molecular Weight , Spectrophotometry, UltravioletABSTRACT
Vechsler technique was applied to study 30 children with hemophilia aged 5 to 15 years. Tentative data showed no mental retardation in patients. Instead, their intellectual development was higher than that of control subjects (50 healthy adolescents). This issue should be further investigated and the data be used in education, choice of profession and occupation in these patients, i.e., their combined rehabilitation.
Subject(s)
Hemophilia A/psychology , Intelligence , Psychomotor Performance/physiology , Adolescent , Cerebral Hemorrhage/etiology , Cerebral Hemorrhage/psychology , Child , Hemophilia A/complications , Humans , Intelligence Tests , MaleSubject(s)
Blood Coagulation Disorders/congenital , Blood Platelet Disorders/diagnosis , Thrombasthenia/diagnosis , Adolescent , Blood Coagulation Disorders/blood , Blood Coagulation Disorders/diagnosis , Child , Child, Preschool , Diagnosis, Differential , Female , Hemophilia A/blood , Hemophilia A/diagnosis , Humans , Male , Thrombasthenia/blood , von Willebrand Diseases/blood , von Willebrand Diseases/congenital , von Willebrand Diseases/diagnosisSubject(s)
Blood Coagulation Disorders/congenital , Hemophilia A/therapy , Adolescent , Adult , Blood Coagulation Disorders/diagnosis , Blood Coagulation Disorders/therapy , Blood Coagulation Factors/therapeutic use , Blood Transfusion , Hemophilia A/diagnosis , Hemophilia B/diagnosis , Hemophilia B/therapy , Hemostatics/therapeutic use , HumansSubject(s)
Hemophilia A/complications , Knee Joint/abnormalities , Adolescent , Child , Child, Preschool , Hemarthrosis/etiology , Hemophilia B/complications , Humans , Infant , Male , RecurrenceABSTRACT
Results of chemical synovectomy of knee joints with 70 per cent ethyl alcohol were analyzed in patients with hemophilia. The chemical synovectomy proved to be effective at early stages of hemophilic arthropathy and may be used in order to prevent progress of hemophilic arthropathy in patients with recurrent hemarthroses.
Subject(s)
Hemarthrosis/prevention & control , Hemophilia A/complications , Synovial Membrane/drug effects , Adolescent , Adult , Child , Child, Preschool , Ethanol , Follow-Up Studies , Hemarthrosis/etiology , Humans , Knee Joint , Punctures/methods , RecurrenceSubject(s)
Contracture/therapy , Hemarthrosis/complications , Hemophilia A/complications , Knee Joint , Child , Combined Modality Therapy , Humans , Male , Massage , Physical Therapy Modalities , TractionSubject(s)
Antisepsis/methods , Kanamycin/administration & dosage , Tooth Extraction/methods , Adolescent , Adult , Aged , Antisepsis/adverse effects , Child , Child, Preschool , Evaluation Studies as Topic , Female , Hemostatic Techniques , Humans , Kanamycin/adverse effects , Male , Middle Aged , Tooth Extraction/adverse effectsABSTRACT
The work summarises experiences with the surgical and orthopedical treatment of 504 patients with hemophilia in the period from 1960 to 1980. It was shown that in most cases errors in the diagnosis and treatment of patients with hemophilia resulted from insufficient knowledge by the surgeons of coagulology questions. The advantages of using laser scalpels were noted in operations on patients with hemophilia allowing to reduce the intraoperative blood loss and to cut down the application of scarce hemostatic drugs.