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1.
Proc Soc Exp Biol Med ; 149(1): 219-22, 1975 May.
Article in English | MEDLINE | ID: mdl-167374

ABSTRACT

Levamisole was tested to determine whether the drug could reduce metastases by HSV-1-transformed cells in a model hamster system. The results presented reveal an inhibition of metastases to the lungs even when the drug is inoculated after development of subcutaneous tumors at the site of inoculation of the cells.


Subject(s)
Cell Transformation, Neoplastic , Levamisole/therapeutic use , Neoplasm Metastasis/drug therapy , Simplexvirus , Animals , Cell Line , Cricetinae , Injections, Intraperitoneal , Injections, Subcutaneous , Levamisole/administration & dosage , Lung/pathology , Neoplasm Transplantation , Neoplasms, Experimental , Time Factors , Transplantation, Homologous
2.
Pol Arch Weter ; 18(2): 201-15, 1975.
Article in Polish | MEDLINE | ID: mdl-16296028

ABSTRACT

Studies were carried out to evaluate and choose the best methods to produce Chlamydial antigens for CFT. The antigens were prepared by the following 4 methods: Beer's method using placentas of ewes infected with Chlamydia: from infected chicken embryos by means of an original own method and by the method of Gyulai at al. (as modified by the author); by the author's method using bull testicles infected with orchitis granulomatosa. Chlamydial antigens obtained in these experiments were active in CFT with some positive Chlamydial sera. The results obtained indicated that the method of Gyulai at al. as modified by the author would be the most useful one under Polish conditions for the production of Chlamydial antigen used in CFT. This test was used for serological diagnosis of Chlamydia infections in cattle and sheep.


Subject(s)
Antibodies, Bacterial/blood , Antigens, Bacterial/immunology , Cattle Diseases/diagnosis , Chlamydia Infections/diagnosis , Sheep Diseases/diagnosis , Animals , Antibody Specificity , Cattle , Cattle Diseases/immunology , Cattle Diseases/prevention & control , Chlamydia Infections/immunology , Sheep , Sheep Diseases/immunology , Sheep Diseases/prevention & control
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