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1.
Revmatologiia (Mosk) ; (3): 3-7, 1990.
Article in Russian | MEDLINE | ID: mdl-1965930

ABSTRACT

The radiological method was used to study the level of prostaglandins E + E, GF2 alpha and LTB4 in the blood plasma and the synovial fluid in 138 children with rheumatoid and other arthritis and noninflammatory diseases of the joints. The role of PGE + A and LTB4 in the pathogenesis of arthritis and low participation of PGF2 have been established. Determination of prostanoids in biological fluids can be used as an additional laboratory index to reveal the general and local activity of the pathological process in rheumatoid and other arthritis and distinguish them from noninflammatory diseases of the joints.


Subject(s)
Arthritis, Juvenile/metabolism , Dinoprost/metabolism , Leukotriene B4/metabolism , Prostaglandins E/metabolism , Synovial Fluid/metabolism , Adolescent , Arthritis, Juvenile/etiology , Child , Child, Preschool , Female , Humans , Male
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