Subject(s)
Hypothyroidism/complications , Infertility, Female/therapy , Prolactin/blood , Sella Turcica/diagnostic imaging , Thyroxine/therapeutic use , Adult , Female , Humans , Hypothyroidism/diagnostic imaging , Hypothyroidism/drug therapy , Infertility, Female/blood , Infertility, Female/etiology , Pregnancy , Pregnancy, Multiple , Radiography , Thyrotropin/blood , TripletsABSTRACT
This is the first reported fatal case of cytomegalic inclusion disease in a pregnant woman. The 28-year-old woman died after cesarean section for cephalopelvic disproportion. The diagnosis of cytomegalic inclusion disease was made at autopsy by finding enlarged pneumocytes with typical intranuclear inclusions, positive direct immunofluorescence on the lung tissue with antibody specific for cytomegalovirus, and retrospective serologic titers of 1:64 for the virus. The time of the infection is unclear, but the absence of infection in the newborn may suggest an onset late in pregnancy; there was no evidence of disease before labor and cesarean section.
Subject(s)
Cytomegalovirus Infections , Puerperal Disorders/etiology , Adult , Antibodies, Viral/analysis , Cytomegalovirus/immunology , Cytomegalovirus Infections/diagnosis , Cytomegalovirus Infections/pathology , Female , Humans , Pregnancy , Pulmonary Alveoli/ultrastructureABSTRACT
At the Mayo Clinic from 1962 through 1973, 592 cesarean sections were done among 16,181 deliveries (3.7%); 48% were primary procedures, and 52% were performed because of previous cesarean delivery. Regional anesthesia using epidural block recently has replaced a balanced general anesthesia as the anesthesia of choice for cesarean sections. Although the low cervical operation was performed in most cases, the classic operation and cesarean hysterectomy were used when indicated. In our series, prophylactic antibiotic therapy failed to decrease the maternal morbidity, and the most frequent causes of neonatal mortality were prematurity and respiratory problems.
