The Capability of Raman Microspectroscopy to Differentiate Printing Inks.

This study applies Raman microspectroscopy to differentiate the chemical components in printing inks of different brands, colors, and type using the 532 nm and 785 nm excitation wavelengths. Spectra were collected from 319 inks (78 inkjet, 76 toner, 79 offset, and 86 intaglio) representing various colors. Comparisons were performed to calculate discrimination capability percentages for each ink type. Overall, Raman microspectroscopy differentiates according to the following hierarchy: intaglio (96%), inkjet (92%), offset (90%), and toner (61%). The ability of Raman microspectroscopy to differentiate between same-colored inks from different brands was dependent on the color and ink analyzed. Based on ink color, the discrimination capability ranged from 75 to 94% (inkjet), 0 to 86% (toner), and 0 to 77% (offset). Copper phthalocyanine was detected in cyan inks and various intaglio inks, while carbon black was identified in black inkjet, offset, and intaglio inks.

Prolactin serum concentrations during aripiprazole treatment in youth.

OBJECTIVE: This study aimed to: document the extent of the reduction of serum prolactin (PRL) levels induced by aripiprazole (ARI) treatment in children and adolescents, compare this effect by age group, and shed light on this phenomenon. METHODS: PRL serum levels in unmedicated subjects were compared to those in subjects treated with aripiprazole to calculate the rate of subnormal PRL levels during aripiprazole treatment. Next, a literature search was performed to better understand the effects of dopaminergic drugs on PRL levels by age group. RESULTS: Sixty percent of those treated with aripiprazole exhibited subnormal PRL serum levels versus 8% of unmedicated subjects. The rate of PRL subnormality in response to aripiprazole was half as frequent in adolescents and was minimal in adults. The drug-induced reduction of PRL serum levels became more prominent with increasing doses of aripiprazole and with an increased treatment duration. CONCLUSIONS: With the increasing use of aripiprazole in the United States population, it is important that future research be conducted to explore the potential sequelae of subnormal PRL serum levels in children and adolescents.

Age-grouped differences in bipolar mania.

OBJECTIVE: This review of published studies compares scores on individual items of mania rating scales that systematically recorded symptom severity in persons diagnosed with bipolar disorder to identify age-grouped differences. METHODS: An extensive literature search identified item scores from mania rating scales, with a particular emphasis on baseline Young Mania Rating Scale (YMRS) item scores in published double-blind, placebo-controlled studies of bipolar I manic disorder. These baseline YMRS item scores were assessed as a proportion of the total YMRS score and compared by age group. Additional YMRS item/total scores in subjects with bipolar spectrum disorders were added to expand the analysis. RESULTS: Preadolescents with bipolar disorder had significantly higher YMRS item scores than adolescents on aggression, irritability, and motor activity. Young Mania Rating Scale baseline item scores relative to the YMRS total score revealed that adolescents diagnosed with bipolar I mania scored comparatively higher than did adults on YMRS aggression and irritability items, whereas adults with bipolar I manic disorder scored comparatively higher on the grandiosity and sexual interest items. Age-grouped findings from subjects diagnosed with bipolar I, II, and Not Otherwise Specified (NOS) disorders yielded similar age-grouped results. CONCLUSION: In age-grouped YMRS item assessments of bipolar mania, anger dyscontrol was most prominent for youth, whereas disordered thought content was paramount for adults.

Socioepidemiology of cigarette smoking among Cambodian Americans in Long Beach, California.

We examined the prevalence of cigarette smoking among Cambodian Americans in Long Beach, California. A stratified random sample of 1,414 adult respondents was selected from 15 census tracts with high concentrations of Cambodian Americans. The prevalence of current smokers was 13.0%; the sex-specific prevalence of smoking was 24.4% for men and 5.4% for women. The mean age of the sample was 50.5 years; about 60% of the respondents were women. The survey response rate was 90.5% among households in which respondents self-identified as Cambodian American, and at least one person completed the survey. Significant covariates of current smoking were gender, age, education, marital status, and health status. The prevalence of smoking among Cambodian men was higher than among other males in California. Culturally-tailored interventions should consider demographic characteristics of the target population as well as the high level of respect given to religion, elders, and peers.

Analysis of acculturation, sex, and heavy alcohol use in Latino college students.

24% of 917 students at California State University Long Beach who completed an alcohol use survey in 2002 (73% response) identified themselves as Latino. Because measures of acculturation reported in most adult studies positively correlated with alcohol use and sex, it was hypothesized that these associations might also apply to Latino college students. With increasing levels of acculturation, women but not men in this Latino college sample reported significantly greater occurrence of heavy drinking, positive attitudes about drinking, and perception that most of their friends use alcoholic beverages.