1.
Chem Commun (Camb)
; 48(44): 5440-2, 2012 Jun 04.
Article
in English
| MEDLINE
| ID: mdl-22534735
ABSTRACT
For the very first time, highly efficient synthesis of DNA-peptide hybrids to scaffold self-assembled nanostructures is described. Oligonucleotide conjugation to the diphenylalanine dipeptide triggers a morphological transition from fibrillar to vesicular structures which may potentially be used as delivery vehicles, since they exhibit pH triggered release.