ABSTRACT
Literature data and results of our own register have indicate that hypertension is one of the most common risk factor in patients with ischemic heart disease (IHD) who have undergone coronary artery bypass grafting (CABG). But despite proven benefits of control of hypertension after CABG adherence of patients to corresponding recommendations remains low. Fixed combinations of antihypertensive drugs are associated with better compliance. In 30 IHD patients after CABG we studied effects of fixed lisinoprillamlodipine combination. This combination was safe and had high antihypertensive activity. Practically all patients responded to therapy and achieved target level of arterial pressure.
Subject(s)
Amlodipine/administration & dosage , Coronary Artery Bypass , Coronary Artery Disease/complications , Hypertension/drug therapy , Lisinopril/administration & dosage , Postoperative Care/methods , Adult , Aged , Antihypertensive Agents/administration & dosage , Blood Pressure/drug effects , Coronary Artery Disease/surgery , Dose-Response Relationship, Drug , Drug Therapy, Combination , Female , Follow-Up Studies , Humans , Hypertension/complications , Hypertension/physiopathology , Male , Middle Aged , Patient Compliance , Prospective Studies , Retrospective Studies , Treatment OutcomeABSTRACT
Literature data and results of our own register have indicate that hypertension is one of the most common risk factor in patients with ischemic heart disease (IHD) who have undergone coronary artery bypass grafting (CABG). But despite proven benefits of control of hypertension after CABG adherence of patients to corresponding recommendations remains low. Fixed combinations of antihypertensive drugs are associated with better compliance. In 30 IHD patients after CABG we studied effects of fixed lisinopril/amlodipine combination. This combination was safe and had high antihypertensive activity. Practically all patients responded to therapy and achieved target level of arterial pressure.
