The heart-break of social rejection versus the brain wave of social acceptance.

The effect of social rejection on cardiac and brain responses was examined in a study in which participants had to decide on the basis of pictures of virtual peers whether these peers would like them or not. Physiological and behavioral responses to expected and unexpected acceptance and rejection were compared. It was found that participants expected that about 50% of the virtual judges gave them a positive judgment. Cardiac deceleration was strongest for unexpected social rejection. In contrast, the brain response was strongest to expected acceptance and was characterized by a positive deflection peaking around 325 ms following stimulus onset and the observed difference was maximal at fronto-central positions. The cardiac and electro-cortical responses were not related. It is hypothesized that these differential response patterns might be related to earlier described differential involvement of the dorsal and ventral portion of the anterior cingulate cortex.

Dissociation between medial frontal negativity and cardiac responses in the ultimatum game: Effects of offer size and fairness.

In the present study, we examined the role of fairness and offer size on brain and cardiac responses in the ultimatum game (UG). Twenty healthy volunteers played the role of responder in a computerized version of the UG in which the fairness and size of the offers were systematically varied. Both fairness and size of the offer influenced the acceptance rates in a predictable way, leading to fewer accepted unfair and low offers. Only unfair high, but not unfair low offers were accompanied by a medial frontal negativity. An unexpected stronger cardiac deceleration to fairer offers was found, which was not affected by the size of the offers. Cardiac and electrocortical measures showed a different relation with performance, and both measures were correlated only modestly. This dissociation between cardiac responses and brain potentials is discussed in terms of a possible differential sensitivity to effects of stimulus probability and violation of the social rules.