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1.
Laryngoscope ; 130(2): E35-E38, 2020 02.
Article in English | MEDLINE | ID: mdl-30953390

ABSTRACT

OBJECTIVES: The aim of this study was to investigate changes in olfactory function after smoking cessation. METHODS: We conducted a cross-sectional study involving 28 volunteers who were admitted to the smoking cessation section of our hospital. Olfactory tests were performed immediately before smoking cessation and 45 days after smoking cessation. The duration of smoking and the number of cigarettes smoked per day were noted. RESULTS: The mean duration of smoking was 25.5 ± 12 years, and the participants smoked 21.6 ± 6.6 cigarettes per day. There was a significant improvement in odor discrimination, odor identification, and TDI scores (i.e., the total score of odor threshold, odor discrimination, and odor identification tests) 45 days after smoking cessation (P = .003, P = .002, and P < .001, respectively). Furthermore, a statistically significant negative correlation was found between the duration of cigarette smoking and the Sniffin' Sticks olfactory tests performed after smoking cessation, namely odor discrimination, odor identification, and TDI (P = .008, P = .002, P = .001, respectively). CONCLUSION: A significant improvement was observed in odor discrimination, odor identification, and TDI scores after smoking cessation. However, this improvement was inversely associated with the duration of smoking, indicating that a longer duration of smoking may result in an insufficient improvement after smoking cessation. LEVEL OF EVIDENCE: 4 Laryngoscope, 130:E35-E38, 2020.


Subject(s)
Smell/physiology , Smoking Cessation , Adult , Aged , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Young Adult
2.
Ear Nose Throat J ; 99(2): 124-127, 2020 Feb.
Article in English | MEDLINE | ID: mdl-31608685

ABSTRACT

Smoking is known to increase laryngeal inflammation and laryngopharyngeal reflux (LPR), which cause laryngeal irritation. Thus, the aim of this study is to evaluate the changes in the symptoms and the findings of laryngeal irritation in smokers after a smoking cessation period. The reflux symptom index (RSI) and the reflux finding score (RFS) were used for evaluating the symptoms and findings of laryngeal irritation in smokers. Endoscopic examination of the laryngeal structures for RFS and symptom inquiry for RSI were performed at the beginning of the study and after a 2 months of cigarette cessation period. This study was carried out in 24 volunteers (14 female and 10 male), between the ages of 24 and 62 years. When we compared the results of RSI and RFS that were performed before and after the cigarette cession period, we found that there was a significant improvement both in RSI and in RFS (P < .001 and P < .001, respectively). Also, there was significant correlation between the cigarette smoking period and RFS score that was determined at the beginning of the study (P = .006, r = .54). A significant improvement was found both in RSI and in RFS after smoking cessation period, which might be the evidence of improvement in laryngeal irritation possibly caused by inflammation due to smoking and LPR. A significant positive correlation was found between smoking period and RFS, especially with vocal fold edema and posterior commissure hypertrophy.


Subject(s)
Cigarette Smoking/therapy , Laryngitis/physiopathology , Laryngopharyngeal Reflux/physiopathology , Smoking Cessation , Adult , Cigarette Smoking/adverse effects , Cohort Studies , Female , Humans , Laryngitis/etiology , Laryngitis/pathology , Laryngopharyngeal Reflux/etiology , Laryngopharyngeal Reflux/pathology , Laryngoscopy , Male , Middle Aged , Prospective Studies , Young Adult
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