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Malays J Pathol ; 29(2): 91-4, 2007 Dec.
Article in English | MEDLINE | ID: mdl-19108400

ABSTRACT

Invasive Neisseria meningitidis infection is rare but carries a high mortality rate. The carriage rate in the normal population is around 10% and can be higher in confined populations. A study on the prevalence of carriage of N. meningitidis was conducted among 3195 army recruits after 2 months of intensive training in an army camp. N. meningitidis was isolated from 37.0% of these recruits. Two hundred and ten of N. meningitidis isolates were subjected to serogrouping and 100 to antibiotic sensitivity testing by the disc diffusion method and E-test for penicillin. Ten (4.8%) of 210 Neisseria meningitidis serogrouped belonged to serogroup W135, 3.33% serogroup A and 81.4% belonged to either serogroup X, Y or Z. With the agar disc diffusion method, all the N. meningitidis showed susceptiblity to chloramphenicol, rifampicin, cefotaxime and levofloxacin; 85% of the strains were resistant to cotrimoxazole and 12.5% resistant to penicillin. However, based on minimum inhibitory concentration, none of the Neisseria meningitidis tested was resistant to penicillin.


Subject(s)
Anti-Bacterial Agents/pharmacology , Drug Resistance, Bacterial , Meningococcal Infections/transmission , Neisseria meningitidis/drug effects , Neisseria meningitidis/genetics , Adolescent , Adult , Female , Humans , Male , Meningococcal Infections/epidemiology , Microbial Sensitivity Tests , Military Personnel
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