Robots at your doorstep: acceptance of near-future technologies for automated parcel delivery.

The logistics and delivery industry is undergoing a technology-driven transformation, with robotics, drones, and autonomous vehicles expected to play a key role in meeting the growing challenges of last-mile delivery. To understand the public acceptability of automated parcel delivery options, this U.S. study explores customer preferences for four innovations: autonomous vehicles, aerial drones, sidewalk robots, and bipedal robots. We use an Integrated Nested Choice and Correlated Latent Variable (INCLV) model to reveal substitution effects among automated delivery modes in a sample of U.S. respondents. The study finds that acceptance of automated delivery modes is strongly tied to shipment price and time, underscoring the importance of careful planning and incentives to maximize the trialability of innovative logistics options. Older individuals and those with concerns about package handling exhibit a lower preference for automated modes, while individuals with higher education and technology affinity exhibit greater acceptance. These findings provide valuable insights for logistics companies and retailers looking to introduce automation technologies in their last-mile delivery operations, emphasizing the need to tailor marketing and communication strategies to meet customer preferences. Additionally, providing information about appropriate package handling by automated technologies may alleviate concerns and increase the acceptance of these modes among all customer groups.

In-person, pick up or delivery? Evolving patterns of household spending behavior through the early reopening phase of the COVID-19 pandemic.

Consumer reactions to COVID-19 pandemic disruptions have been varied, including modifications in spending frequency, amount, product categories and delivery channels. This study analyzes spending data from a sample of 720 U.S. households during the start of deconfinement and early vaccine rollout to understand changes in spending and behavior one year into the pandemic. This paper finds that overall spending is similar to pre-pandemic levels, except for a 28% decline in prepared food spending. More educated and higher income households with children have shifted away from in-person spending, whereas politically conservative respondents are more likely to shop in-person and via pickup.

Shifting Mobility Behaviors in Unprecedented Times: A Multigroup MIMIC Model Investigating Intentions to Use On-Demand Ride Services During the COVID-19 Pandemic.

The spread of COVID-19 has been a major disruptive force in people's everyday lives and mobility behavior. The demand for on-demand ride services, such as taxis and ridehailing, has been specifically affected given both restrictions in service operations and users' concerns about virus transmission in shared vehicles. In the early months of the pandemic, demand for these modes decreased by as much as 80%. This study examines intentions to use on-demand ride services in the early lockdown stage of the pandemic in the United States, a period of unprecedented mobility reductions, changing household routines and transforming travel behaviors. Using data from a survey disseminated in June 2020 to 700 U.S. respondents, we use multigroup MIMIC (Multiple Indicator Multiple Cause) models to investigate the stated shift in intentions to use on-demand modes of travel. By using group-based segmentation we control for variation in ridership intentions according to personal, household, attitudinal factors, and pandemic experiences. The results point to a reduction across the board in the likelihood of using on-demand mobility associated with a significant COVID-19 effect. Beyond this general decrease, several groups are found to have more positive intentions, including younger adults, urban residents, graduate-degree holders, and people of Hispanic, Latino, Asian, and Pacific Islander ethnicities/races. The attitudinal effect of "tech-savviness" drives higher user intentions, revealing indirect effects of gender, education, and age. Multigroup analysis provides further evidence of potential COVID-triggered shifts in on-demand ridership intentions. The most significant drops in likelihood are observed for younger respondents (below 45), Black compared with all other racial/ethnic status, and for past users of on-demand mobility. This latter result is somewhat surprising, as riders who are younger and more experienced with on-demand travel are more likely to have been users in the past, but also more likely to reduce use during the pandemic. To conclude, we discuss the need to investigate pandemic experiences, risk attitudes, and circumstances to understand evolving mobility behavior and specific service model impacts.

For whom did telework not work during the Pandemic? understanding the factors impacting telework satisfaction in the US using a multiple indicator multiple cause (MIMIC) model.

The COVID-19 pandemic required employees and businesses across the world to rapidly transition to work from home over extended periods, reaching what is likely the upper bound of telework in many sectors. Past studies have identified both advantages and disadvantages of teleworking. The pandemic experience offers a unique opportunity to examine employees' experiences and perceptions of telework given the broad participation duration and extent. While employer strategies will play a major role in defining the future forms and adoption of telework, employee preferences and constraints, such as access to appropriate technology to work from home or the home environment, are also going to be important factors. Using data from a U.S. representative sample of 318 working adults, this study uses a Multiple Indicator Multiple Cause Model (MIMIC) to understand employee satisfaction with telework. The presented model links telework satisfaction with experienced and perceived benefits and barriers related to telework, and hence provide a causal structure to our understanding of telework satisfaction. We also present an ordered probit model without latent variables that help us understand the systematic heterogeneity in telework satisfaction across various socio-demographic groups. The results suggest younger and older aged individuals experienced/perceived lower benefits and higher barriers to teleworking compared to middle aged individuals. The results also suggest a disproportionate impact on Hispanic or Latino and Black respondents as well as on those with children attending online school from home. Accordingly, this study highlights important factors impacting telework adoption that employers and policy makers should consider in planning future work arrangements and policies in a post-pandemic world.

Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes.

Uncontrolled release of Ca(2+) from the sarcoplasmic reticulum (SR) contributes to the reperfusion-induced cardiomyocyte injury, e.g. hypercontracture and necrosis. To find out the underlying cellular mechanisms of this phenomenon, we investigated whether the opening of mitochondrial permeability transition pores (MPTP), resulting in ATP depletion and reactive oxygen species (ROS) formation, may be involved. For this purpose, isolated cardiac myocytes from adult rats were subjected to simulated ischemia and reperfusion. MPTP opening was detected by calcein release and by monitoring the ΔΨ(m). Fura-2 was used to monitor cytosolic [Ca(2+)](i) or mitochondrial calcium [Ca(2+)](m), after quenching the cytosolic compartment with MnCl(2). Mitochondrial ROS [ROS](m) production was detected with MitoSOX Red and mag-fura-2 was used to monitor Mg(2+) concentration, which reflects changes in cellular ATP. Necrosis was determined by propidium iodide staining. Reperfusion led to a calcein release from mitochondria, ΔΨ(m) collapse and disturbance of ATP recovery. Simultaneously, Ca(2+) oscillations occurred, [Ca(2+)](m) and [ROS](m) increased, cells developed hypercontracture and underwent necrosis. Inhibition of the SR-driven Ca(2+) cycling with thapsigargine or ryanodine prevented mitochondrial dysfunction, ROS formation and MPTP opening. Suppression of the mitochondrial Ca(2+) uptake (Ru360) or MPTP (cyclosporine A) significantly attenuated Ca(2+) cycling, hypercontracture and necrosis. ROS scavengers (2-mercaptopropionyl glycine or N-acetylcysteine) had no effect on these parameters, but reduced [ROS](m). In conclusion, MPTP opening occurs early during reperfusion and is due to the Ca(2+) oscillations originating primarily from the SR and supported by MPTP. The interplay between Ca(2+) cycling and MPTP promotes the reperfusion-induced cardiomyocyte hypercontracture and necrosis. Mitochondrial ROS formation is a result rather than a cause of MPTP opening.