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Nat Prod Rep ; 37(2): 246-275, 2020 02 01.
Article in English | MEDLINE | ID: mdl-31204423

ABSTRACT

Covering: January 2013 to September 2018Sulfur-containing natural products are a large class of significant functional molecules. Many of these compounds exhibit potent biological activities and pharmacological properties; in fact, some of them have been developed into important drugs. The total synthesis of sulfur-containing natural products is a subject that has long attracted significant attention from synthetic organic chemists; to achieve this goal, various methods have been developed over the past years. This review surveys total syntheses of sulfur-containing natural products that introduce sulfur atoms using different sulfurization agents to construct related sulfur-containing moieties.


Subject(s)
Biological Products/chemical synthesis , Sulfur/chemistry , Alkaloids/chemical synthesis , Alkaloids/chemistry , Biological Products/chemistry , Carbolines/chemical synthesis , Carbolines/chemistry , Disaccharides/chemical synthesis , Disaccharides/chemistry , Disulfides/chemistry , Enediynes/chemical synthesis , Enediynes/chemistry , Ferrichrome/analogs & derivatives , Ferrichrome/chemical synthesis , Ferrichrome/chemistry , Indole Alkaloids/chemical synthesis , Indole Alkaloids/chemistry , Indoles/chemical synthesis , Indoles/chemistry , Isothiocyanates/chemical synthesis , Isothiocyanates/chemistry , Molecular Structure , Peptides, Cyclic/chemical synthesis , Peptides, Cyclic/chemistry , Piperazines/chemistry , Sulfates/chemistry , Sulfoxides/chemical synthesis , Sulfoxides/chemistry , Thiazoles/chemical synthesis , Thiazoles/chemistry
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