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Keio J Med ; 56(4): 124-9, 2007 Dec.
Article in English | MEDLINE | ID: mdl-18185028

ABSTRACT

Chemoradiotherapy improves therapeutic outcome in many different types of cancer. However, there is concern about the occurrence of delayed complications, as patients are surviving longer. Because patients with esophageal cancer receive a wide range of irradiation field to the mediastinum and the heart, they may have delayed complications of heart and lung functions as previously reported in Hodgkin's disease. We presented a case of death related to uncontrollable pleural and pericardial effusions in a patient with advanced cancers of the esophagus and stomach who achieved a complete remission following chemoradiotherapy and salvage gastric resection, focusing on detailed pathophysiological conditions related to concurrent chemoradiotherapy.


Subject(s)
Carcinoma, Squamous Cell/drug therapy , Esophageal Neoplasms/drug therapy , Esophageal Neoplasms/pathology , Pericardial Effusion/complications , Pleural Effusion/complications , Stomach Neoplasms/drug therapy , Stomach Neoplasms/pathology , Aged , Carcinoma, Squamous Cell/complications , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/surgery , Esophageal Neoplasms/complications , Esophageal Neoplasms/surgery , Fatal Outcome , Humans , Male , Neoplasm Staging , Stomach Neoplasms/complications , Stomach Neoplasms/surgery , Treatment Failure
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