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Eur J Pediatr ; 168(4): 501-2, 2009 Apr.
Article in English | MEDLINE | ID: mdl-18629535

ABSTRACT

We report a 3-year-old boy with enterohemorrhagic Escherichia coli (EHEC) O157-associated hemolytic uremic syndrome (HUS). His anemia was associated with decreased reticulocyte count and persisted after the recovery from HUS. Superinfection of parvovirus B19 (PVB19) was proven by a transient febrile episode associated with IgM antibodies to the virus and the delayed appearance of IgG antibodies and typical rashes. We conclude that PVB19 infection could induce severe persistent anemia in EHEC-associated HUS. Reticulocytopenia is a clue to the diagnosis in such cases.


Subject(s)
Anemia/virology , Escherichia coli Infections/complications , Escherichia coli O157/isolation & purification , Hemolytic-Uremic Syndrome/complications , Parvoviridae Infections/virology , Parvovirus B19, Human/isolation & purification , Superinfection/virology , Anemia/diagnosis , Anemia/therapy , Child, Preschool , Erythrocyte Transfusion , Escherichia coli Infections/diagnosis , Hemolytic-Uremic Syndrome/diagnosis , Humans , Male , Parvoviridae Infections/diagnosis , Parvoviridae Infections/therapy , Superinfection/diagnosis
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