ABSTRACT
Maxwell's and heat transfer equations were coupled and solved to determine the heating characteristics of an RF rectangular resonant cavity applicator for hyperthermia before the clinical stage. A simple human model with blood flow and a fat layer was constructed. The region unaffected by tumor was shielded from electromagnetic fields by using conductive caps. The surface of the human model that was exposed to the electromagnetic fields was cooled with pure water bolus. Calculated results show that this applicator can heat a deep-seated tumor.
Subject(s)
Hyperthermia, Induced/instrumentation , Neoplasms/physiopathology , Neoplasms/therapy , Radiofrequency Therapy , Therapy, Computer-Assisted/methods , Adipose Tissue/pathology , Algorithms , Computer Simulation , Computer-Aided Design , Equipment Design , Hot Temperature , Humans , Hyperthermia, Induced/methods , Models, Biological , Models, Statistical , Software , Therapy, Computer-Assisted/instrumentation , TransducersABSTRACT
The heating characteristics of an RF rectangular cavity applicator for hyperthermic treatment that targets deep-seated tumors were investigated numerically and experimentally. In the numerical study, Maxwell's equations and heat transfer equations were solved for a dielectric phantom with and without blood flow. Conductive caps attached to the dielectric phantom to shield the non-tumor regions. The experimental study showed the validity and possibility of heating deep-seated tumors. Thus, the rectangular resonant cavity applicator with an L-type antenna can heat deep-seated tumors.
Subject(s)
Hyperthermia, Induced/instrumentation , Models, Biological , Neoplasms/physiopathology , Neoplasms/therapy , Radiofrequency Therapy , Therapy, Computer-Assisted/methods , Transducers , Computer Simulation , Computer-Aided Design , Equipment Design , Equipment Failure Analysis , Hot Temperature , Humans , Hyperthermia, Induced/methods , Therapy, Computer-Assisted/instrumentationABSTRACT
Electromagnetic and heat-transfer equations were solved to investigate a radio frequency (RF) rectangular resonant cavity applicator. The possibility of heating a deep-seated tumor was demonstrated. A torso-shaped dielectric phantom was made. It has electrical constants resembling those of human muscle. Several L-type antennas were made and placed at appropriate locations to heat a deep region. Measured results agreed with the calculated results. Results show that the rectangular resonant cavity applicator with the L-type antennas can heat deep-seated tumors.
