Subject(s)
Dysentery, Bacillary/diagnosis , Dysentery, Bacillary/microbiology , Military Personnel , Shigella sonnei/immunology , Adolescent , Adult , Antibodies, Bacterial/blood , Antibody Specificity , Antigen-Antibody Complex/blood , Humans , Immunoglobulins/blood , Male , O Antigens/blood , Prognosis , Russia , Time FactorsABSTRACT
The antigen-specific method for the determination of specific immune complexes in the blood serum of patients with acute Sonne dysentery has been developed on the basis of the enzyme-linked immunosorbent assay with the use of reagents manufactured in the USSR. The possibility of the early prognostication of prolonged carrier state by using the proposed method for the determination of the level of specific circulating immune complexes has been shown.
Subject(s)
Antibody Specificity/immunology , Antigen-Antibody Complex/blood , Dysentery, Bacillary/immunology , Epitopes/immunology , Shigella sonnei/immunology , Acute Disease , Enzyme-Linked Immunosorbent Assay/instrumentation , Enzyme-Linked Immunosorbent Assay/methods , Humans , MaleABSTRACT
The authors investigated the clinical importance of determination of the O-antigen in coprofiltrates of patients with acute Sonne dysentery by means of immunoenzymatic analysis. It was found that use of immunoenzymatic analysis is justified for etiological diagnosis of dysentery as well as with the purpose of forecasting recurrence of the disease.
Subject(s)
Antigens, Bacterial/analysis , Dysentery, Bacillary/diagnosis , Shigella sonnei/immunology , Acute Disease , Diagnosis, Differential , Enterocolitis/diagnosis , Feces/analysis , Humans , Male , O Antigens , Shigella flexneri/immunology , Time FactorsSubject(s)
Anti-Bacterial Agents/therapeutic use , Dysentery, Bacillary/drug therapy , Enteritis/drug therapy , Escherichia coli Infections/drug therapy , Salmonella Food Poisoning/drug therapy , Drug Resistance, Microbial , Escherichia coli/drug effects , Humans , Salmonella/drug effects , Shigella/drug effectsABSTRACT
Sensitivity of 92 strains of the causative agent of pseudotuberculosis isolated in the Ukraine was studied with respect to 26 antibacterial drugs. It was found that the strains of the pseudotuberculous bacteria were sensitive to 17 drugs, i.e. benzylpenicillin, ampicillin, carbenicillin, cephaloridin, chloramphenicol, tetracycline, streptomycin, neomycin, monomycin, kanamycin, gentamicin, polymyxin, colistin, furadontin, nalidixic acid, sulfisoxazol and septrin. No differences in the sensitivity of the strains isolated in various districts of the Ukraine and from various sources were found. By their antibiotic sensitivity the strains isolated in the Ukraine did not differ from the cultures isolated in other districts of the USSR and abroad.
Subject(s)
Anti-Bacterial Agents/pharmacology , Yersinia Infections/microbiology , Yersinia pseudotuberculosis Infections/microbiology , Yersinia/drug effects , Animals , Dose-Response Relationship, Drug , Humans , Microbial Sensitivity Tests , UkraineABSTRACT
Resistance of 1280 strains of Salmonella of various serological types isolated in the Zakarpatskaya region within 1967-1976 was studied with respect to benzylpenicillin, streptomycin tetracycline, levomycetin, monomycin, neomycin, erythromycin and oleandomycin. An Increase in the resistance of Salmonella to streptomycin, tetracycline, levomycetin, monomycin and neomycin was shown. During the last years Salmonellae carrying 4-8 resistance determinants were spreading in the region. Among S. typhimurium strains with 7-8 resistance determinants predominated (58.8 per cent). The cases of salmonollosis were mainly due to these strains.
