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BMJ Case Rep ; 15(8)2022 Aug 09.
Article in English | MEDLINE | ID: mdl-35944940

ABSTRACT

Kimura's disease is a rare, benign entity that causes subcutaneous angioblastic lymphoid hyperplasia with eosinophilia. It usually presents with subcutaneous lymphoid swellings with regional lymphadenopathy and salivary gland masses. Kimura's disease is frequently associated with renal involvement, which includes proteinuria and nephrotic syndrome as the most common presentations. This report presents a case of a man in his early 20s with a swelling in the medial aspect of the distal left arm with two previous episodes of nephrotic syndrome. Multiple enlarged axillary lymph nodes and epitrochlear nodes were noted. Ultrasonography revealed a mixed echogenic mass with enlarged lymph nodes. MRI showed a heterogeneous hyperintense lesion. Image-guided fine-needle aspiration showed multiple lymphocytes and eosinophils suggestive of Kimura's disease. The swelling was surgically excised under general anaesthesia. Histopathology of the excised mass confirmed the diagnosis of Kimura's disease.


Subject(s)
Angiolymphoid Hyperplasia with Eosinophilia , Kimura Disease , Lymphadenopathy , Nephrotic Syndrome , Angiolymphoid Hyperplasia with Eosinophilia/complications , Angiolymphoid Hyperplasia with Eosinophilia/diagnosis , Angiolymphoid Hyperplasia with Eosinophilia/surgery , Arm/pathology , Chest Pain/pathology , Humans , Kimura Disease/complications , Kimura Disease/diagnosis , Kimura Disease/surgery , Lymph Nodes/pathology , Lymphadenopathy/diagnostic imaging , Lymphadenopathy/pathology , Male , Nephrotic Syndrome/complications
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