ABSTRACT
Introducción: El carcinoma papilar es la neoplasiamaligna más frecuente de la glándula tiroides. La mayoríade los tumores son de bajo riesgo (89%) con un índice decurabilidad elevado y mortalidad del 1,8%. La tendencia ametastatizar a distancia es sumamente infrecuente e inusualen cerebro. Caso clínico: Paciente femenino de 52 años queconsulta por presentar cuadro de hipertensión endocraneanade corto tiempo de evolución y bocio nodular grado II-III notratado. En la resonancia magnética nuclear de cerebro seobservaron múltiples imágenes nodulares, homogéneas conhipercaptación y edema perilesional El estudio histopatológicode las lesiones nodulares en cerebro mostró la imagende un Carcinoma Papilar metastásico no clásico con célulascolumnares-altas y expresión de tiroglobulina. La pacientefallece posterior a la cirugía. Discusión: El diagnóstico inicialcomo metástasis cerebral de un carcinoma papilar deorigen tiroideo es inusual. Este tipo de evolución se observacomo en nuestro caso en pacientes de alto riesgo, mayores,con bocios de gran tamaño y variantes histológicas de Carcinomapapilar no clásicas agresivas (AU)
Introduction: Papillary thyroid carcinoma is the commonestmalignant neoplasm in the thyroid gland. The mostof the tumours are low risk (89%) with high cure rate andlow mortality (1,8%). Distant metastases are extremely rare.Brain metastases are unusual. Case report: A 52-year oldwoman presented with a short evolution history of highintracranial pressure symptoms, including vomiting, headacheand general clinical worsening. She had grade II-III goitrewithout treatment. Magnetic resonance imaging followingintravenous gadolinium contrast, demonstrated multiplehomogeneous enhancing masses and perilesionaloedema were noted. Histopathology confirmed diagnosticof non classic papillary thyroid carcinoma, tall cell andcolumnar cell variant. Twelve days after surgery, the patientdied. Discussion: Metastases of papillary thyroid carcinomagenerally occur to regional lymph nodes. Brain metastasesare described in 0.1-5% of patients. Aggressive variantof carcinoma and older patients are related to this evolution.At the moment therapeutic modalities are being discussed (AU)
Subject(s)
Humans , Male , Middle Aged , Thyroid Neoplasms/pathology , Brain Neoplasms/secondary , Carcinoma, Papillary/secondaryABSTRACT
Objective: to describe the case of a medulla oblongata benign teratoma associated with endocrinological disorders. Description: a 23 years old female patient presented with headache, vomiting, dizzines, ataxia, amenorrhea and galactorrhea, progressive during the last 5 years. MRI showed a fourth ventricle tumoral lesion that involved the medulla oblongata with hydrocephalus. Intervention: first a ventriculo peritoneal shunting was performed. One week later through a midline approach a microsurgical complete removal was done. Postoperative outcome was good. MRI 6 months later was free of tumor. After one year the neurological examination was normal. Conclusion: teratomas of the medulla oblongata are rare lesions. Surgery is the treatment of choice
Subject(s)
Adult , Female , Amenorrhea , Brain Stem Neoplasms , Galactorrhea , TeratomaABSTRACT
Objective: to describe the case of a medulla oblongata benign teratoma associated with endocrinological disorders. Description: a 23 years old female patient presented with headache, vomiting, dizzines, ataxia, amenorrhea and galactorrhea, progressive during the last 5 years. MRI showed a fourth ventricle tumoral lesion that involved the medulla oblongata with hydrocephalus. Intervention: first a ventriculo peritoneal shunting was performed. One week later through a midline approach a microsurgical complete removal was done. Postoperative outcome was good. MRI 6 months later was free of tumor. After one year the neurological examination was normal. Conclusion: teratomas of the medulla oblongata are rare lesions. Surgery is the treatment of choice (AU)
