Selective recovery of gold and silver from electronic wastes through a sequential process of Qalkari and room-temperature hydrometallurgy.

This work was focused on the selective recovery of gold and silver from electronic wastes using a sequential process of pyrometallurgy (Qalkari) and room-temperature hydrometallurgy. In the first step, electronic wastes underwent Qalkari recycling, yielding tablets containing precious elements (Qalkari furnace product) and melting slag (Qalkari furnace waste). In the subsequent hydrometallurgy phase, the nitric acid concentration and the input solid amount were optimized for the effective room-temperature recovery of gold. Due to the successful separation of precision elements and disturbing substances in Qalkari, the gold recovery efficiency of 99.99% was obtained at the acid concentration of 50% (v/v) and the solid input of 15% (w/v). Afterwards, HCl, NH4Cl, and NaCl were used for silver recovery from the Qalkari-processed gold-recovered leaching solution, leading to the efficiency of 99.99%. But NH4Cl was recognized as the most effective precipitant as it promises the most enhanced potential for the possible subsequent recovery of palladium. In conclusion, this study draws the effectiveness of Qalkari in recycling electronic wastes, with a significant impact on the efficiency of succeeding room-temperature hydrometallurgical processes for gold and silver recovery within a reasonable leaching time.

Cell loaded hydrogel containing Ag-doped bioactive glass-ceramic nanoparticles as skin substitute: Antibacterial properties, immune response, and scarless cutaneous wound regeneration.

An ideal tissue-engineered dermal substitute should possess angiogenesis potential to promote wound healing, antibacterial activity to relieve the bacterial burden on skin, as well as sufficient porosity for air and moisture exchange. In light of this, a glass-ceramic (GC) has been incorporated into chitosan and gelatin electrospun nanofibers (240-360 nm), which MEFs were loaded on it for healing acceleration. The GC was doped with silver to improve the antibacterial activity. The bioactive nanofibrous scaffolds demonstrated antibacterial and superior antibiofilm activities against Gram-negative and Gram-positive bacteria. The nanofibrous scaffolds were biocompatible, hemocompatible, and promoted cell attachment and proliferation. Nanofibrous skin substitutes with or without Ag-doped GC nanoparticles did not induce an inflammatory response and attenuated LPS-induced interleukin-6 release by dendritic cells. The rate of biodegradation of the nanocomposite was similar to the rate of skin regeneration under in vivo conditions. Histopathological evaluation of full-thickness excisional wounds in BALB/c mice treated with mouse embryonic fibroblasts-loaded nanofibrous scaffolds showed enhanced angiogenesis, and collagen synthesis as well as regeneration of the sebaceous glands and hair follicles in vivo.

Performance comparison of PLA- and PLGA-coated porous bioceramic scaffolds: Mechanical, biodegradability, bioactivity, delivery and biocompatibility assessments.

Bioceramics, particularly calcium phosphates, bioactive glasses, and crystalline silicates, are a principal group of biomaterials employed for the regeneration of damaged tissues and therapeutic delivery. The development of ceramic tissue engineering scaffolds with an appropriate combination of mechanical and biological properties is still one of the key challenges in this field. In this regard, the deposition of polymeric coatings on the scaffolds is a simple and effective approach to reinforce their functions. Among different polymers, the influences of biodegradable aliphatic polyester coatings, especially polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA), over the performance of the scaffolds have been investigated in numerous research. This review paper provides a comprehensive comparison of PLA- and PLGA-coated bioceramic scaffolds which are mainly employed in bone tissue engineering. It is concluded that both the polymers enhance the mechanical behaviors of the scaffolds, but control their biodegradability, bioactivity, and delivery kinetics, where PLA acts almost more influentially than PLGA in comparison. However, the response of biocompatibility to this surface treatment is condition-dependent and requires case-by-case experiments to be determined accurately.

Biphasic calcium phosphate microspheres in biomedical applications.

Biphasic calcium phosphate (BCP) microspheres benefit from, on the one hand, a desired shape offering improved flowability and injectability to fill complex-shaped bone defects and on the other hand, a promising combination of bioresorbability, bioactivity, biocompatibility, osteogenesis and angiogenesis. The biofunctional characteristics of BCP microspheres are mainly controlled by varying the constitute phase ratio, porosity and surface roughness, which are all determined by the used production route and its parameters. In this paper, the manufacturing methods, properties and applications of BCP microspheres are reviewed and concluded in terms of future work directions to develop their uses in biomedicine, particularly in bone tissue regenerative and delivery applications.

Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry.

Surface modification, particularly coatings deposition, is beneficial to tissue-engineering applications. In this work, bioactive glass/zirconium titanate composite thin films were prepared by a sol-gel spin-coating method. The surface features of the coatings were studied by scanning electron microscopy, atomic force microscopy, and spectroscopic reflection analyses. The results show that uniform and sound multilayer thin films were successfully prepared through the optimization of the process variables and the application of carboxymethyl cellulose as a dispersing agent. Also, it was found that the thickness and roughness of the multilayer coatings increase nonlinearly with increasing the number of the layers. This new class of nanocomposite coatings, comprising the bioactive and inert components, is expected not only to enhance bioactivity and biocompatibility, but also to protect the surface of metallic implants against wear and corrosion.

In vitro electrochemical corrosion and cell viability studies on nickel-free stainless steel orthopedic implants.

The corrosion and cell viability behaviors of nanostructured, nickel-free stainless steel implants were studied and compared with AISI 316L. The electrochemical studies were conducted by potentiodynamic polarization and electrochemical impedance spectroscopic measurements in a simulated body fluid. Cytocompatibility was also evaluated by the adhesion behavior of adult human stem cells on the surface of the samples. According to the results, the electrochemical behavior is affected by a compromise among the specimen's structural characteristics, comprising composition, density, and grain size. The cell viability is interpreted by considering the results of the electrochemical impedance spectroscopic experiments.