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Curr Pharm Des ; 29(42): 3385-3399, 2023.
Article in English | MEDLINE | ID: mdl-38099527

ABSTRACT

Cervical cancer is one of the most prevalent malignancies among females and is correlated with a significant fatality rate. Chemotherapy is the most common treatment for cervical cancer; however, it has a low success rate due to significant side effects and the incidence of chemo-resistance. Curcumin, a polyphenolic natural compound derived from turmeric, acts as an antioxidant by diffusing across cell membranes into the endoplasmic reticulum, mitochondria, and nucleus, where it performs its effects. As a result, it's been promoted as a chemo-preventive, anti-metastatic, and anti-angiogenic agent. As a consequence, the main goal of the present review was to gather research information that looked at the link between curcumin and its derivatives against cervical cancer.


Subject(s)
Curcumin , Uterine Cervical Neoplasms , Female , Humans , Curcumin/pharmacology , Curcumin/therapeutic use , Uterine Cervical Neoplasms/drug therapy , Plant Extracts/pharmacology , Antioxidants , Curcuma
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