ABSTRACT
Elaioconiosis is a work-related acneiform dermatosis which affects the exposed skin of individuals working with oils or greases. Its incidence has decreased with the introduction of personal protective equipment, personal hygiene measures and the cleaning of work clothes. Although not a rare disease, elaioconiosis is seldom reported in the literature, particularly in Brazil. Sufferers need to take time off work to proceed with the prolonged treatment to resolve the lesions caused by this condition.
Subject(s)
Dermatitis, Occupational/etiology , Hand Dermatoses/chemically induced , Industrial Oils/toxicity , Dermatitis, Occupational/pathology , Hand Dermatoses/pathology , Humans , Male , Middle Aged , Sick LeaveABSTRACT
A fifty-five year old Caucasian male presented with infiltrated plaques and nodules on the left leg. The lesions had been present for 6 months. He presented associated cardiopathy, nephropathy and endocrinopathy. Histopathological and immunohistochemical examinations confirmed the diagnosis of cutaneous diffuse B cell lymphoma. CD 20, CD 79a and Ki-67 were positive. Chemotherapy with cyclophosphamide, adriamycin and vincristine promoted partial remission.
Subject(s)
Lymphoma, Large B-Cell, Diffuse/pathology , Skin Neoplasms/pathology , Antineoplastic Combined Chemotherapy Protocols , Biomarkers, Tumor/blood , Cyclophosphamide/therapeutic use , Doxorubicin/therapeutic use , Humans , Lymphoma, Large B-Cell, Diffuse/drug therapy , Male , Middle Aged , Remission Induction , Skin Neoplasms/drug therapy , Vincristine/therapeutic useABSTRACT
Elaioconiose é uma dermatose ocupacional do tipo acneiforme que afeta as áreas expostas de trabalhadores que lidam com óleos ou graxas. Atualmente, com o uso dos equipamentos de proteção individual, medidas de higiene pessoal e lavagem dos uniformes de trabalho, sua incidência diminuiu. Apesar de não ser uma doença rara, é pouco relatada na literatura, principalmente na nacional. Seu tratamento é lento e para a resolução das lesões, requer o afastamento do trabalhador de suas atividades laborativas.
Elaioconiosis is a work-related acneiform dermatosis which affects the exposed skin of individuals working with oils or greases. Its incidence has decreased with the introduction of personal protective equipment, personal hygiene measures and the cleaning of work clothes. Although not a rare disease, elaioconiosis is seldom reported in the literature, particularly in Brazil. Sufferers need to take time off work to proceed with the prolonged treatment to resolve the lesions caused by this condition.
Subject(s)
Humans , Male , Middle Aged , Dermatitis, Occupational/etiology , Hand Dermatoses/chemically induced , Industrial Oils/toxicity , Dermatitis, Occupational/pathology , Hand Dermatoses/pathology , Sick LeaveABSTRACT
Paciente do sexo masculino de 55 anos com placas e nódulos infiltrados exuberantes em membro inferior esquerdo há seis meses. Cardiopatia, nefropatia e endocrinopatia associadas. O exame histopatológico, acrescido da imunoistoquímica, confirma linfoma cutâneo difuso de células B. Marcadores CD-20, CD-79a e Ki-67 foram positivos. A quimioterapia com ciclofosfamida, adriamicina e vincristina promoveu remissão parcial.
A fifty-five year old Caucasian male presented with infiltrated plaques and nodules on the left leg. The lesions had been present for 6 months. He presented associated cardiopathy, nephropathy and endocrinopathy. Histopathological and immunohistochemical examinations confirmed the diagnosis of cutaneous diffuse B cell lymphoma. CD 20, CD 79a and Ki-67 were positive. Chemotherapy with cyclophosphamide, adriamycin and vincristine promoted partial remission.
Subject(s)
Humans , Male , Middle Aged , Lymphoma, Large B-Cell, Diffuse/pathology , Skin Neoplasms/pathology , Antineoplastic Combined Chemotherapy Protocols , Cyclophosphamide/therapeutic use , Doxorubicin/therapeutic use , Lymphoma, Large B-Cell, Diffuse/drug therapy , Remission Induction , Skin Neoplasms/drug therapy , Biomarkers, Tumor/blood , Vincristine/therapeutic useABSTRACT
BACKGROUND: Synthetic permanent fillers for soft-tissue augmentation have acquired an important role in cosmetic improvement of patients with facial aging, facial atrophic scars, or lipoatrophy leading to facial defects. Polymethylmethacrylate (PMMA) is a filler introduced to the market as one option for long-lasting treatment. PMMA microspheres are purified, and the particles are larger than 20 microm. The product used as a filler has proven to be safe, effective, and long lasting. OBJECTIVE: To determine the efficacy and safety of PMMA as a facial filler. METHODS: Two hundred sixty-six patients (aged 17-72; 154 women) received injections of PMMA to correct facial defects. The number of sessions ranged from one to four, with an interval of 40 to 60 days between applications. RESULTS: Seventy-nine subjects (30%) had facial atrophy related to HIV infection, 159 (60%) had photoaging signs with deep wrinkles and atrophic areas, 25 (9%) had depressive scars from acne process, and three (1%) had residual depressions from lupus profundus. The results were satisfactory and long lasting. Side effects were transient. No late complications were observed. CONCLUSION: PMMA used for the treatment of atrophy, depressions, and facial wrinkles has been shown to be effective, long lasting, safe, and gratifying to patients and physicians.
Subject(s)
Face/surgery , Polymethyl Methacrylate , Prostheses and Implants , Surgery, Plastic/methods , Adolescent , Adult , Aged , Brazil , Female , Follow-Up Studies , Humans , Male , Middle AgedABSTRACT
A co-infecção leishmaniose tegumentar americana e AIDS é de relato recente na literatura, observando-se diversidade quanto ao comportamento clínico e imunológico destes pacientes. Relatamos quatro casos acompanhados no Hospital Universitário de Brasília, com diagnóstico de infecçäo por parasitas do gênero Leishmania e pelo vírus da imunodeficiência humana, ilustrando diferentes apresentaçöes clínicas, evoluções e respostas terapêuticas
Subject(s)
Adult , Female , Humans , Male , Middle Aged , AIDS-Related Opportunistic Infections/diagnosis , Acquired Immunodeficiency Syndrome/diagnosis , Leishmaniasis, Diffuse Cutaneous/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/drug therapy , Leishmaniasis, Diffuse Cutaneous/complications , Leishmaniasis, Diffuse Cutaneous/drug therapyABSTRACT
The co-infection American cutaneous leishmaniasis and AIDS has recently been described in the literature, observing differences between the clinical and immunological behavior of these patients. Four cases are reported here, attended at the Brasilia University Hospital, with diagnoses of infection by Leishmania species and immunodeficiency virus, with a view to illustrating the clinical presentations, course and therapeutic responses.
Subject(s)
AIDS-Related Opportunistic Infections/diagnosis , Acquired Immunodeficiency Syndrome/diagnosis , Leishmaniasis, Diffuse Cutaneous/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/drug therapy , Adult , Female , Humans , Leishmaniasis, Diffuse Cutaneous/complications , Leishmaniasis, Diffuse Cutaneous/drug therapy , Male , Middle AgedABSTRACT
O sarcoma de Kaposi (SK) é neoplasia rara, inicialmente descrita por Moritz Kaposi em 1872. São relatados quatro formas clinicopatológicas peculiares. O interesse em todos os aspectos dessa doença vem aumentando gradualmente pela emergência do vírus da imunodeficiência humana (HIV), que freqëntemente se associa ao sarcoma de Kaposi. Apesar de descobertas recentes importantes, o manuseio do SK permanece um desafio. O desconhecimento de sua patogênese impede o desenvolvimento de um tratamento eficaz. Os autores relatam um caso da forma clássica do sarcoma de Kaposi, enfatizando os aspectos clínicos, diagnósticos e terapêuticos
