ABSTRACT
Significance of the tissues oedema and its elimination in the course of inflammation and the wound healing was investigated. There were analyzed the results of treatment of 68 patients, suffering inflammatory and necrotic affection of soft tissues, including 65 a lower one, 3 an upper. In 47 observations the affection course was an acute, while in 18 chronic. In 36 patients (control group) a local and systemic antibacterial therapy were conducted, and in accordance to indications surgical interventions; in 32 (main group) this treatment was added with tight bandaging of the extremity, using elastic bandage. Tight squeezing of tissues with the oedema elimination on background of an adequate antibacterial therapy and surgical sanation of purulent-necrotic focus is accompanied by arrest of infiltrative and exudative stages of an acute inflammation, promotes an active course of the inflammation proliferative stage. While treatment of chronic cutaneous defect, the application of tight squeezing have promoted the granulating shaft resolution, the granulation growth in the wound and its boundary epithelization.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Compression Bandages , Edema/therapy , Necrosis/therapy , Soft Tissue Infections/therapy , Surgical Wound Infection/therapy , Acute Disease , Adult , Aged , Chronic Disease , Edema/microbiology , Edema/pathology , Edema/surgery , Extremities/microbiology , Extremities/pathology , Extremities/surgery , Female , Humans , Male , Middle Aged , Necrosis/microbiology , Necrosis/pathology , Necrosis/surgery , Re-Epithelialization/drug effects , Re-Epithelialization/physiology , Soft Tissue Infections/microbiology , Soft Tissue Infections/pathology , Soft Tissue Infections/surgery , Surgical Wound Infection/microbiology , Surgical Wound Infection/pathology , Surgical Wound Infection/surgery , Treatment OutcomeABSTRACT
The results of prostaglandin E1 et systemic antibacterial therapy use in 1836 patients, suffering purulent-necrotic affection of foot, were summarized. There was established, that cefuroxym constitutes the first line preparation for the ostheoarthropathy focus elimination, when the affection is limited and the patient state is stable, and meronem--for extended affection and unstable patient's state. In the pronounced ischemia of the foot the initial administration of cefepim is the most effective. For purulent-necrotic affection as a consequence of the foot wounding, erysipelas or operative intervention it is expedient to use carbapenem or meropenem. The systemic antibacterial therapy administration had promoted significant reduction of the treatment duration and improvement of its result.
