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1.
Arch Soc Esp Oftalmol ; 92(3): 145-148, 2017 Mar.
Article in English, Spanish | MEDLINE | ID: mdl-27402450

ABSTRACT

CLINICAL CASE: A 43-year-old woman in remission from T- cell acute lymphoblastic leukaemia was referred to our hospital with suspected leukaemic retinitis. The funduscopic examination of her left eye revealed multifocal yellow-white peripheral retinitis and retinal haemorrhage. The patient was treated for cytomegalovirus retinitis after an extended haematological investigation showed no abnormalities. Initial improvement was followed by papillitis in the left eye and motility restriction in the right eye. Magnetic resonance and lumbar puncture confirmed leukaemia relapse. Specific treatment was initiated with complete resolution. DISCUSSION: Ocular involvement may precede haematological leukaemia relapse. Physicians should be alerted when ocular symptoms appear in these cases.


Subject(s)
Cytomegalovirus Retinitis/etiology , Leukemic Infiltration , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/complications , Retina/pathology , Adult , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Combined Modality Therapy , Cytarabine/administration & dosage , Female , Granulocyte Colony-Stimulating Factor/administration & dosage , Humans , Idarubicin/administration & dosage , Leukemic Infiltration/drug therapy , Leukemic Infiltration/radiotherapy , Papilledema/etiology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/radiotherapy , Recurrence , Retinal Hemorrhage/etiology , Vidarabine/administration & dosage , Vidarabine/analogs & derivatives
2.
Arch Soc Esp Oftalmol ; 91(9): 439-41, 2016 Sep.
Article in English, Spanish | MEDLINE | ID: mdl-27036528

ABSTRACT

CLINICAL CASE: Seven-year-old male patient, affected by xeroderma pigmentosum (XP) who was referred to ophthalmology due to the presence of numerous tumours in his left eye that affected the eyelids and conjunctiva. He had a tumour in his lower eyelid that affected the free edge, creating a secondary ectropion, and several lesions with a melanocytic appearance in conjunctiva. A resection of the eyelid tumour and the conjunctival lesions were performed by placing a skin graft and amniotic membrane, respectively, as covering. DISCUSSION: XP patients have high probability of developing eye tumours. A thorough ophthalmic examination is necessary to establish an early diagnosis.


Subject(s)
Carcinoma, Basal Cell/surgery , Eyelid Neoplasms/surgery , Eyelids/surgery , Neoplasms, Radiation-Induced/surgery , Plastic Surgery Procedures/methods , Xeroderma Pigmentosum/surgery , Amnion/transplantation , Carcinoma, Basal Cell/etiology , Child , Eyelid Neoplasms/etiology , Humans , Male , Neoplasms, Multiple Primary/etiology , Neoplasms, Radiation-Induced/etiology , Skin Transplantation
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