1.
Talanta
; 174: 733-737, 2017 Nov 01.
Article
in English
| MEDLINE
| ID: mdl-28738650
ABSTRACT
This paper shows the ability of simple modified screen-printed devices for the electrochemical detection of ascorbic acid in different samples, including serum samples. Even if the presence of uric acid does not greatly affect the analysis of ascorbic acid using screen-printed carbon electrodes modified by gold nanoparticles, dopamine must be considered an interferent. Thus, the joint determination of the three compounds has been set out using methods of multivariate calibration. The validated models, built by partial least squares regressions, have been used to determine the concentration of ascorbic acid, dopamine and uric acid of spiked serum samples, with successful results.