ABSTRACT
Oral tryptyline was evaluated clinically in the treatment of 14 male and 16 female patients; ages were 17 to 52 years the males and 32 to 59 years the females. Four had had no prior antidepressive treatment and the rest had had medication with poor to no results. The study ran for 12 weeks, with 15 patients showing improvement by the fourth week, 8 by the fifth week, 1 by the sixth; 5 showed no change. Side effects disappeared adjusting the dosage. Seventeen patients showed total improvement, 8 moderate improvement and 5 showed no change.
Subject(s)
Amitriptyline/therapeutic use , Depression/drug therapy , Administration, Oral , Adolescent , Adult , Amitriptyline/adverse effects , Drug Evaluation , Female , Humans , Male , Middle AgedABSTRACT
Sixty patients, ages 15 to 59, mostly neurotics, were used to study the effect of mepiprazol on the anxiety syndrome. The drug was compared to oxacepam. The results with mepiprazol were considered acceptable with no important collateral effects.