ABSTRACT
A 13-year-old Saudi boy was referred to the paediatric endocrinology clinic for evaluation of rapidly progressive goitre with weight loss of 6 months duration. A clinical diagnosis of possible thyroid malignancy was made. On exploration the mass was found to be tuberculous in origin, attached to the thyroid gland, and responded to partial excision and anti-tuberculous chemotherapy. Tuberculosis should be considered in the differential diagnosis of anterior midline neck masses.
Subject(s)
Antitubercular Agents/therapeutic use , Goiter/diagnosis , Thyroid Diseases/diagnosis , Thyroid Diseases/drug therapy , Tuberculosis, Endocrine/diagnosis , Tuberculosis, Endocrine/drug therapy , Adolescent , Diagnosis, Differential , Humans , Male , Thyroid Diseases/surgery , Tuberculosis, Endocrine/surgeryABSTRACT
Sheathed microfilariae (mean length 278 +/- 10 microns SEM; mean width 7.2 +/- 0.8 microns) were detected in the blood of 7/14 housed camels (Camelus dromedarius). Microfilaraemic camels of either sex were inappetent, lethargic, reluctant to move and exhibited weakness in the hind limbs; some remained in sternal recumbency. Cardiac disorders, orchitis and skin nodules were conspicuously absent. The microfilariae showed a biphasic pattern in the blood that peaked at 20:00 and plateaued between 04:00 and 06:00. Adult filarial worms were recovered from the mesenteric and femoral arteries. Marked clinical improvement within 1-2 weeks was seen in three camels treated at 10:00 with a single subcutaneous injection of 0.2 mg/kg of ivermectin. These camels became amicrofilaraemic 2-5 days after treatment and remained so for the length of the observation period (133 days). Treatment of two camels at the time of high microfilaraemia (06:30) resulted in adverse reaction and death.
