ABSTRACT
Inflammatory pseudo tumor (IP) is an infrequent process with benign evolution in most cases whose etiology and pathogenesis are unknown. It usually affects young men and children, in whom the macroscopic lesion can mimic a malignant process, which is ruled out after biopsy. Therefore, the diagnosis of certainty is histological and treatment consists of corticosteroids, leaving resection for cases in which biopsy is not possible or in which it produces local complications. We present a case of an inflammatory pseudo tumor with special corticodependence that began as a long-term periodic fever and splenic focal lesion that required splenectomy for its diagnosis and that, after decreasing the corticosteroid regimen, presented recurrences at the cerebellar and systemic level requiring the association of various immunosuppressants and rituximab to achieve remission. As a result of this case, we have performed an analysis of all the pseudo tumors diagnosed in adults in the hospitals of the province of Malaga, and it has been compared with that described in the bibliography.
Subject(s)
Immunosuppressive Agents , Neoplasms , Adult , Male , Child , Humans , Splenectomy , Adrenal Cortex Hormones , RituximabABSTRACT
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Subject(s)
Humans , Soft Tissue Infections/diagnosis , Immunocompetence , Fasciitis/diagnosis , Soft Tissue Infections/etiology , Soft Tissue Infections/classification , Anti-Bacterial Agents/therapeutic use , Fasciitis/drug therapy , Staphylococcus aureus/pathogenicityABSTRACT
La tuberculosis diseminada es un proceso que suele afectar a pacientes inmunodeprimidos. Su manifestación inicial como fascitis necrosante es excepcional, sobre todo si no se asocia a tuberculosis ósea. El diagnóstico de esta rara complicación requiere un alto índice de sospecha por parte del clínico y el aislamiento del Mycobacterium tuberculosis en el tejido muscular, ya que los síntomas pueden remedar a la enfermedad de base, por lo que la biopsia muscular se presenta como la principal herramienta diagnóstica. Presentamos el caso de un paciente que recibía terapia inmunodepresora por síndrome nefrótico asociado a nefropatía por cambios mínimos y que desarrolló esta rara complicación, donde el diagnóstico se hizo basándose en los hallazgos de la biopsia muscular. También se realiza una revisión de los casos similares encontrados en la literatura médica(AU)
Disseminated tuberculosis is a process that mainly affects immunocompromised hosts. Its initial appearance as necrotising fasciitis is exceptional especially if it is not associated to a bone disorder. The diagnosis of this rare complication requires a high degree of suspicion and the evidence of Mycobacterium tuberculosis in the muscular tissue, since the symptoms may mimic the underlying illness itself, for this reason the most sensitive method for demonstrating tuberculous infection is a muscular biopsy. Here we present the case of a patient who was receiving immunosuppressant therapy for nephrotic syndrome by minimal lesion glomerulonephritis and who developed this rare complication, where diagnosis was made by muscular biopsy. So we do a review of similar case reports in the literatura(AU)
Subject(s)
Humans , Male , Middle Aged , Fasciitis, Necrotizing/diagnosis , Tuberculosis/diagnosis , Immunocompromised Host , Mycobacterium tuberculosis/isolation & purification , Nephrotic Syndrome/drug therapy , Immunosuppressive Agents/adverse effectsABSTRACT
Disseminated tuberculosis is a process that mainly affects immunocompromised hosts. Its initial appearance as necrotising fasciitis is exceptional especially if it is not associated to a bone disorder. The diagnosis of this rare complication requires a high degree of suspicion and the evidence of Mycobacterium tuberculosis in the muscular tissue, since the symptoms may mimic the underlying illness itself, for this reason the most sensitive method for demonstrating tuberculous infection is a muscular biopsy. Here we present the case of a patient who was receiving immunosuppressant therapy for nephrotic syndrome by minimal lesion glomerulonephritis and who developed this rare complication, where diagnosis was made by muscular biopsy. So we do a review of similar case reports in the literature.
