1.
Drug Discov Ther
; 7(1): 43-5, 2013 Feb.
Article
in English
| MEDLINE
| ID: mdl-23524943
ABSTRACT
A case of idiopathic dilated cardiomyopathy with an arrhythmic storm refractory to the usual antiarrhythmic therapy will be reported. The idiopathic structural heart disease of the patient is a vulnerable anatomic substrate in itself, for electrical instability and reentry mechanism, because of heterogeneous areas of scarred myocardium and low left ventricle ejection fraction. In this case, the ranolazine administration was safe and effective for the prevention of further electrical storms.
Subject(s)
Acetanilides/therapeutic use , Anti-Arrhythmia Agents/therapeutic use , Cardiomyopathy, Dilated/drug therapy , Piperazines/therapeutic use , Tachycardia, Ventricular/drug therapy , Acetanilides/administration & dosage , Aged , Anti-Arrhythmia Agents/administration & dosage , Cardiomyopathy, Dilated/complications , Cardiomyopathy, Dilated/diagnosis , Defibrillators, Implantable , Electrocardiography , Heart Rate/drug effects , Humans , Male , Piperazines/administration & dosage , Ranolazine , Tachycardia, Ventricular/complications , Tachycardia, Ventricular/diagnosis , Treatment Outcome , Ventricular Dysfunction, Left/complications , Ventricular Dysfunction, Left/diagnosis , Ventricular Dysfunction, Left/drug therapy
2.
Minerva Med
; 104(1): 115-7, 2013 Feb.
Article
in English
| MEDLINE
| ID: mdl-23392545