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J Am Acad Dermatol ; 32(2 Pt 1): 205-11, 1995 Feb.
Article in English | MEDLINE | ID: mdl-7829704

ABSTRACT

BACKGROUND: Epidemiologic studies indicate that after using soaps and other personal care products, many consumers experience irritation. In 50% of the cases the feelings of skin dryness, itching, and stinging occur in the absence of visible signs of irritation. OBJECTIVE: We sought to determine the relation between self-perceived sensory responses of panelists to cleansing products and clinical signs of irritation. METHODS: A combination of exaggerated arm-washing methods was designed to induce clinical signs of irritation with psychometric techniques developed to quantify sensations. RESULTS: Two studies demonstrated that panelists could reproducibly differentiate between products on the basis of the sensations they felt and that there was a significant correlation (frequently r > 0.80) between these and the observable signs. In the case of skin dryness panelists differentiated products several washing cycles before observable differences were detected. CONCLUSION: Sensory evaluations of irritation yield additional information on soap and detergent irritancy beyond clinical observations and expand understanding of the irritation process.


Subject(s)
Dermatitis, Irritant/etiology , Detergents/adverse effects , Perception/physiology , Sensation/physiology , Skin/drug effects , Soaps/adverse effects , Color , Dermatitis, Irritant/pathology , Dermatitis, Irritant/psychology , Desiccation , Erythema/chemically induced , Erythema/pathology , Erythema/psychology , Female , Forearm , Humans , Pruritus/chemically induced , Pruritus/pathology , Pruritus/psychology , Psychometrics , Reproducibility of Results , Self-Assessment , Skin/pathology , Skin Diseases/chemically induced , Skin Diseases/pathology , Skin Diseases/psychology , Water Loss, Insensible/drug effects
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